Karim, EshabaMeghla, Sanjita RahmanSarkar, Christina ChaityAfrozah, Jannatul2026-08-222026-08-2220262026-01ID 20346011ID 20346020ID 20346028https://hdl.handle.net/10361/29435This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2026.Cataloged from PDF version of thesis.Includes bibliographical references (page 33).Paracetamol is one of the most widely used over-the-counter analgesic and antipyretic drug in Bangladesh. Due to its extensive consumption, maintaining consistent tablet quality is essential to ensure therapeutic effectiveness and patient safety. This study aimed to comparatively evaluate the quality control parameters, specifically hardness and friability, of selected oral paracetamol tablet brands available in Bangladesh. A total of fifteen commercially available brands were collected and analyzed using standard in vitro quality control methods. The obtained results were statistically analyzed using one- way ANOVA to assess significant differences among brands and formulations. All tested brands complied with limits for friability and exhibited acceptable hardness values. Statistical analysis indicated no significant differences in hardness and friability between tablets of different doses of paracetamol and tablets with different drug combination (p > 0.05). These findings suggest that the evaluated brands demonstrate satisfactory mechanical integrity33 pagesen-USAttribution-NonCommercial-NoDerivatives 4.0 InternationalBRAC University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission.http://creativecommons.org/licenses/by-nc-nd/4.0/ParacetamolHardnessFriabilityANOVAAntipyretic drugAcetaminophen.Acetaminophen--Technological innovations.Analysis of variance.Pharmacology.Pharmaceutical industry--Bangladesh.Thesis