Haque, Md. AminulRahman, Saqib2020-08-082020-08-0820192019-08ID 15146048http://hdl.handle.net/10361/13923Cataloged from PDF version of thesis report.Includes bibliographical references (pages 57-63).This thesis is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2019.The main purpose of this study was to evaluate and compare the quality control parameters of twelve different brands of ebastine tablets available in Bangladesh. Different in vitro quality parameters including weight variation, % friability, hardness, disintegration time, dissolution profile and potency were assessed according to the compendial procedures. According to BP specification, all tablets of each brand showed % weight variation within the range. All brands showed their friability within the USP designated limit of less than 0.5%. Within 30 minutes, tablets from all brands disintegrated completely which complies with BP and JP specifications and eight out of twelve brands could not meet the first stage dissolution test. Potency was calculated using UV-spectrometric method and tablets from all brands showed potency not less than 90%. The study illustrates that all brands of ebastine tablets showed acceptable results for the experiments performed except 1st stage dissolution test for few brands.63 pagesenBrac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission.EbastineBCS class II drugIn vitro quality evaluationAssay by UV-spectroscopyDissolution profileConventional oral dosage formThesis