Akter, RaushanaraTaki, Ehtesham Sabet2024-06-122024-06-122023-09ID 19346022http://hdl.handle.net/10361/23403Cataloged from the PDF version of the thesis.Includes bibliographical references (pages 62-68).This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023.This study was aimed to assess antioxidant and antidiabetic properties of Lagerstroemia thorell since no previous reports on its bioactivity screening were found during extensive literature search. Antioxidant activity was determined using total phenolic acid and total flavonoid content assays, while antidiabetic property was evaluated by α-amylase inhibition assay. The phytochemical screening confirmed the presence of flavonoids, polyphenols, glycosides, tannins, carbohydrates, steroids, and resins in L. thorelli. L. thorelli exhibited strong antidiabetic activity, inhibiting α-amylase by 93.9 ± 3.429% at the highest concentration, closely resembling the standard's (Glimepiride) 95.36 ± 3.345% inhibition rate. Furthermore, the plant exhibited a moderate level of antioxidant activity, with a phenolic acid content of 45.18 ± 4.138 mg GAE/g at the highest concentration. The findings inferred that L. thorelli can be used as a potent antidiabetic agent. However, further in-vivo studies and clinical trials are warranted to use it for the treatment of diabetes.68 pagesenBrac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission.Phytochemical screeningAntioxidant activityPhenolicsLagerstroemia thorelliAnthocyanins--Health aspects.Thesis