Islam, Md. RabiulBhuiyan, Fahmida Fiaza2026-09-032026-09-0320262026ID 22146004https://hdl.handle.net/10361/29715This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2026.Cataloged from PDF version of thesisIncludes bibliographical references (pages 94-107).In this thesis, interleukin patterns and their involvement in the Generalized Anxiety Disorder (GAD) biological processes are examined. The paper evaluates the presence of inflammatory cytokines in the pathophysiology of anxiety and whether they can be used as a biomarker. The presence of immune imbalance and the severity of anxiety were investigated by comparing the pro-inflammatory and anti-inflammatory cytokines (IL-6, IL-1b, IL-17, and IL-10). The results indicate that patients with GAD have high pro-inflammatory cytokines and low anti-inflammatory controls, which means that there is an inflammatory dominance pattern. The IL-6/IL-10 ratio proved to be an important predictor of immune imbalance associated with the severity of symptoms. These findings back a neuroimmune theory of inflammatory dysregulation interacting with biological systems of stress. The research adds to the growing body of research in psychoneuroimmunology and demonstrates the importance of inflammatory biomarkers in the study and understanding of anxiety as well as in enhancing precision-based mental health studies.107 pagesen-USAttribution-NonCommercial-NoDerivatives 4.0 InternationalBRAC University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission.http://creativecommons.org/licenses/by-nc-nd/4.0/InterleukinAnxiety disorderInflammatory cytokinesBiomarkerDysregulationPsychoneuroimmunologyInterleukin-2.Anxiety disorders.Inflammatory bowel diseases.Cytokines--Pathophysiology.Biochemical markers.Affective disorders.Thesis