Asaduzzaman, MuhammadIslam, Sadatul2025-09-152025-09-1520252025-09ID 21346093http://hdl.handle.net/10361/26748Cataloged from PDF version of thesis.Includes bibliographical references (pages 51-53).This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2025.Antimicrobial resistance (AMR) in Acinetobacter spp. is becoming prevalent and poses a significant danger to worldwide public health. A total of 4247 culture sensitivity data were analysed from BIRDEM General Hospital Microbiology Laboratory, Dhaka, along with patient demographics for the last three years (2022 – 2024) from diverse biological specimens, including urine, pus, blood and other biological fluids. The most prevalent pathogen was Escherichia coli (n=1482), followed by Klebsiella spp. (n=1084), Pseudomonas spp. (n=550), Acinetobacter spp. (n=306) and Staphylococcus aureus (n=215). Highest level of antibiotic resistance was exhibited against ciprofloxacin (88.0%), amoxicillin (75.7%), cefixime (75.3%), and cefuroxime (74.2%). A subset of 18 Acinetobacter spp. clinical isolates was cultured for confirmatory testing by PCR. Among 18 Acinetobacter spp. clinical isolates, 16 were PCR-positive. There was 80% total MDR and 20% was non-MDR. Among the clinical isolates 88.9% (n=16) were MDR. Interestingly, there were a single PDR (n=1) isolate. Complete (100%) resistance was exhibited against ceftriaxone and ceftazidime, followed by amoxicillin (98%), meropenem (95%), and cefixime (94%). Overall findings highlight a deteriorating public health issue that necessitates urgent intervention to halt AMR.53 pagesenBRAC University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission.Antimicrobial resistanceMulti drug resistanceMAR indexKlebsiella sppPublic healthDrug resistance in microorganisms.Multidrug resistance.Public health--Bangladesh.Thesis