Siddique, RomanaSarker, Sujoy2026-07-012026-07-0120202020-10ID 16136007https://hdl.handle.net/10361/28448This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Science in Biotechnology, 2020.Catalogued from PDF version of thesis.Includes bibliographical references (pages 23-26).The use of heavy metals in the tannery industry for leather processing and discharge of untreated effluents from this industry in the environment is a leading challenge to solve. Hence, micro-organism has a great potential to grow in the presence of toxic substances and it is a novel, cost-effective and eco-friendly approach to remove these heavy metals (Cr, Pb, Cu, Zn) from these contaminated sites and safeguard our environment. Toxic substances are hard to degrade, and microbes develop detoxifying mechanisms to counteract these substances' toxic effects. This article reviews the isolation of the heavy metal resistant bacteria and their ability to co-resistant against the antibiotic. Escherichia coli, Staphylococcus sp., Klebsiella sp., Pseudomonas sp. was identified to resist toxic substances to a minimum inhibitory concentration. In some cases, the same isolates showed co-resistance to multiple heavy metals. All the isolates were also resistant to several antibiotics. My study highlights the organisms' physiological color change in response to any stimuli like heavy metals as the media is incorporated with the heavy metals. Besides, interaction with different toxic compounds is still unclear if these patterns of color change are simply the consequences of heavy metals or any underlying factor or enzyme is responsible for the color transformation.26 pagesen-USBRAC University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission.BioremediationTannery industryAntibiotic resistanceHeavy metal resistant bacteriaHeavy metals--Physiological effect.Drug resistance in microorganisms.Thesis