Yasmin, HasinaTrisha, Rabeya Rahman2022-11-172022-11-1720222022-03ID: 17346017http://hdl.handle.net/10361/17583Cataloged from PDF version of thesis report.Includes bibliographical references (pages 31-40).This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022.Cryo-EM is a type of electron microscope that employs the cryomicroscopy technology, which involves cooling materials and examining them under a microscope to create 3D models of proteins. Throughout this COVID-19 pandemic, the development of medicines are critical, and the protein structures of the SARS-CoV-2 virus must be recognized in order to battle COVID 19. Cryo-EM may be used to find protein structural alignments, protein positioning, domain motif interaction with known antiviral medications, and potential therapeutic routes for creating treatments and vaccines. Furthermore, because Cryo-EM allows scientists to examine dynamic models of proteins, it makes it simpler for them to analyze molecules of various shapes and dimensions, which may be a significant benefit over X-ray crystallography. The use of Cryo-EM in medication development for COVID-19 including how future drugs can be designed to counter COVID-19 are discussed in this review paper so that the pandemic can be brought to a close.40 Pagesen-USBrac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission.Drug DiscoveryCryo-EMSARS-CoV-2COVID-19Drug-Protein interactionsElectron microscopy--TechniqueThesis