Yasmin, Professor Dr. HasinaBhuiyan, Jamim2023-07-122023-07-1220222022-09ID: 18346057http://hdl.handle.net/10361/18746Cataloged from PDF version of thesis.Includes bibliographical references (pages 28-31).This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022.Ibuprofen (IBP) is a NSAID, falls under BCS class II drug having poor aqueous solubility (21 mg/L) that may limit its biopharmaceutical behavior in clinical application. The main purpose of this study is to develop dry emulsion formulation of ibuprofen (DE-IBP). DE-IBP was prepared by evaporating a liquid O/W emulsion containing ethyl acetate polymer, polyethylene oxide 600, and medium chain triglyceride as the emulsifying agents. Physicochemical properties of DE-IBP were evaluated using various analytical techniques. The results showed reduced particle size in DE-IBP as well as the crystalline nature of IBP has reduced significantly; which might be beneficial in enhancing the solubility of IBP compared to crystalline IBP. The dissolution studies in water showed improved dissolution of DE-IBP compared to crystalline IBP, with a quick onset of drug release followed by gradual dissolution. Therefore, DE-IBP could be a promising drug delivery strategy to improve the biopharmaceutical behaviors of IBP.31 pagesenBrac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission.Dry emulsion formulationIbuprofenIbuprofen--MedicineThesis