Akter, RaushanaraRajib, Raisha2024-09-092024-09-09© 20242024-04ID 20146011http://hdl.handle.net/10361/24022A thesis submitted to the School of Pharmacy in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2024.Cataloged from PDF version of thesis.Includes bibliographical references (pages 35-40).Plants in the Lythraceae family are well-known for having anti-inflammatory, analgesic, and antidiabetic qualities. However, through a comprehensive literature search it was found that the antidiabetic, analgesic, and CNS depressant properties of Lagerstroemia thorelli (L. thorelli) have not yet been investigated. This research involved the use of the ethanol leaf extract of Lagerstroemia thorelli at doses of 200 mg/kg, 400 mg/kg, and 600 mg/kg in Swiss albino mice. The antidiabetic effect was assessed in alloxan-induced diabetic mice, the analgesic activity was detected using the acetic acid-induced writhing test, and the CNS depressant effect was determined using the hole cross method. The plant extract exhibited a dose-dependent, statistically significant (P<0.01) antidiabetic, remarkable analgesic and CNS depressant properties. Thus, the present study suggests that extract of Lagerstroemia thorelli could be an effective treatment for diabetes.40 pagesenBrac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission.Medicinal plantLagerstroemia thorelliCNS depressantantidiabeticCentral nervous system depressants.Analgesics.Thesis