Chowdhury, Namara MariamFarhana, TasniaMahi, Nabila Tasnim2025-12-182025-12-1820252025-08ID 21346015ID 19346081http://hdl.handle.net/10361/27337Cataloged from PDF version of thesis.Includes bibliographical references (pages 70-73).This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2025.Elaeocarpus Floribundus was evaluated for antidiabetic, anti-inflammatory, and antioxidant potential using three leaf extracts prepared by Buckner filtration (E1), rotary evaporation (E2), and air-drying (E3) and screened in baker’s yeast glucose-uptake, HRBC hypotonichemolysis, and DPPH assays with metformin, diclofenac, and ascorbic acid as benchmarks (triplicates). E2 produced the highest yeast glucose uptake (68.0%), closely matching metformin (68.35%), followed by E3 (59.5%) and E1 (54.4%). In the HRBC assay at 400 μg mL⁻¹, inhibition ranked diclofenac 85.6%, E1 81.7%, E2 81.0%, and E3 43.7%, indicating strong membrane-stabilizing activity for E1/E2. DPPH profiling revealed concentrationdependent scavenging for all extracts; E3 was most potent with IC₅₀ < 10 μg mL⁻¹ and >50% inhibition at 10 μg mL⁻¹, whereas E1 and E2 were moderate (IC₅₀ ≈ 65 and 71 μg mL⁻¹, respectively); ascorbic acid showed IC₅₀ < 10 μg mL⁻¹ and >90% inhibition. Collectively, extraction strategy dictated functional profiles, with E2 strongest on metabolic and membrane endpoints and E3 a superior radical scavenger, supporting subsequent phytochemical standardization, mechanistic evaluation in mammalian systems, and in-vivo validation.92 pagesenBRAC University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission.Elaeocarpus floribundusAntidiabeticsAntioxidantHRBC membrane stabilizationAnti-inflammatory agentsPlant extractsTraditional medicineBioactive compoundsAnti-inflammatory agents.Medicinal plants.Herbs--Therapeutic use.Hypoglycemic agents.Pharmacognosy.Thesis