Haque, Fahim Kabir MonjurulArin, Tanzin RahmanHasan, TasmiahAdry, Shahamida Jahan2025-12-242025-12-2420252025-09ID 19326025ID 19326022ID 19226008http://hdl.handle.net/10361/27370This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Science in Microbiology, 2025.Catalogued from PDF version of thesis.Includes bibliographical references (pages 35-42).This study investigated the prevalence of Staphylococcus aureus (S. aureus) in oral swabs collected from Brac University students and assessed the antibiotic resistance profiles of the isolates. A total of 50 samples were cultured on Mannitol Salt Agar and subsequently on Nutrient Agar. Of these, 32 samples exhibited bacterial growth, with S. aureus identified in 16 cases. The prevalence of S. aureus was higher among male students compared to female students. Polymerase chain reaction (PCR) analysis confirmed the presence of S. aureus, as indicated by distinct 275 bp bands in positive samples. Antibiotic susceptibility testing revealed that 75% of the isolates were resistant to both Ciprofloxacin and Levofloxacin, which are classified as Fluoroquinolones. In contrast, the majority of isolates remained sensitive to Linezolid, Chloramphenicol, and Doxycycline. These findings underscore the necessity for continuous surveillance of oral S. aureus to monitor resistance patterns and guide effective treatment strategies.58 pagesenBRAC University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission.Staphylococcus aureusS. aureusOral swabsAntibiotic resistanceOral cavityAntibiotic susceptibilityResistance patternsPolymerase chain reactionFluoroquinolonesStaphylococcus aureus--Identification.Mouth--Microbiology.Pathogenic bacteria.Thesis