Haque, Md. AminulRadoa, Ramiza Islam2026-04-162026-04-1620252025-11ID 20146069http://hdl.handle.net/10361/27906Cataloged from PDF version of thesis.Includes bibliographical references (pages 28-46).This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2025.Cystic Fibrosis (CF) is a chronic autosomal recessive disease that causes absence or dysfunction of Cystic Fibrosis Transmembrane Conductance Regulator protein (CFTR) that mediates ion channels. CF is a multi-organ disease that affects the function of lung, kidney, and pancreas by causing chronic inflammation, mucus accumulation, infection, loss of function, resulting in morbidity and mortality. CF is a pediatric disease in which patients die in the first year of life but the advancement in the medical field increases the longevity of patients up to 5 decades. Even though CF doesn't have any ultimate cure or prevention method, the advanced medical technology reduces the symptoms and improves the health. Early diagnosis also helps in CF treatment. Recent development of CFTR modulators target the mechanisms of mutation and reverse it and restore function. Also, many other drugs are under clinical trials to check their safety and efficacy46 pagesenBRAC University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission.Transmembrane conductance regulatorProteinIon channelCF treatmentCystic FibrosisCystic fibrosis--Treatment.Molecular pharmacology.Cystic fibrosis--Diagnosis.Thesis