Siam, Mohammad Kawsar SharifAkhter, Tahamina2024-06-092024-06-09©20242024-02ID: 19346005http://hdl.handle.net/10361/23236Cataloged from the PDF version of thesis.Includes bibliographical references (pages 44-51).This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2024.Helicobacter pylori (H. pylori) bacteria is a gram-negative bacteria that has capability to cause serious disease in human stomach by leading into peptic ulcer, mucosal lymph tissue, stomach cancer. According to WHO, it became type I carcinogen bacteria which colonizes and affects gastric mucosa layer of the stomach. Available antibiotics drugs were effective but now-days growing resistance to this particular bacterium. Hence, for such emerging situation a vaccine will be much more effective against bacterium; more convenient and budget friendly option to sufferer. In this study, protein sequence is used with different epitopes of Helper T cells, cytotoxic T cells, B cells to predict multi epitope-based vaccine for protection by computational (immunoinformatics) method.64 pagesenBrac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission.FlaA proteinH. pyloriMulti-epitope vaccineIn-silicoCTLHTLHelicobacter pylori bacteriaVaccinesPathogenic bacteriaThesis