Talukder, MesbahBhuiyan, Tanjina Pioush2025-01-132025-01-13©202320232023-04ID 18346030http://hdl.handle.net/10361/25135Cataloged from PDF version of thesis.Includes bibliographical references (pages 41-43).This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023.Minoxidil, mostly used as a vasodilator was first introduced as an oral drug used to treat high blood pressure. Then gradually minoxidil showed hair darkening of fine body hair as a side effect. This specific side effect led to the development of topical minoxidil. Topical minoxidil is mainly produced as a 2% solution to treat female adrenergic alopecia and a 5% solution for male adrenergic alopecia. But the changes disappeared after stopping its use for a month. Minoxidil is mainly potassium channel opener so it assumes that it causes hyperpolarization and again it's a vasodilator. The mechanism it mainly widening blood vessels and opening potassium channels so it allows more oxygen and nutrients to the hair which causes regrowth of hair. This article will show a complete review of the pharmacokinetics, pharmacodynamics, and mechanism of action, side effects, and clinical efficacy of topical minoxidil.43 pagesenBrac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permissionTopical minoxidilAdrenergic alopeciaHyperpolarizationVasodilatorDihydrotestosteroneMinoxidil--Therapeutic Use.Androgenetic Alopecia.Clinical Trials--Hair Loss Treatments.Thesis