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A review on the role of Epigenetics in Psychiatry: Etiology, contemporary medicine and future perspectives

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15236003_MNS.pdf (433.09 KB)

Date

2020-07

Publisher

BRAC University

Authors

Full item page

URI

http://hdl.handle.net/10361/15075

Citation

Abstract

Psychiatric disorders are complex phenomena that have neurological, genetic and epigenetic bases. The epigenetic underpinnings of such disorders have been discovered and rediscovered in past research and provide a promising ground for drug development involving fewer side effects and faster recovery. This paper illustrates the epigenetics underlying the development of depression, anxiety disorders, and schizophrenia. In addition, it elaborates on epigenetic pharmacotherapy, focusing on HDAC and DNMT inhibitory activities of contemporary medicine and prospective epigenetic drugs.

Keywords

Psychiatric epigenetics, Pharmacology, Drug development, HDAC inhibitor, DNMT inhibitor

Description

Catalogued from PDF version of thesis.
Includes bibliographical references (pages 32-36).
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Science in Biotechnology 2020.

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Department

Department of Mathematics and Natural Sciences

Type

Thesis

Collections

Thesis (Bachelor of Science in Biotechnology)