Renal function assessment for CKD in Type-2 Diabetes patients of Bangladesh: a cross-sectional study

Abstract

Chronic Kidney Disease (CKD) is a major long-term complication of Type 2 diabetes mellitus. The aim of this study was to determine the prevalence of CKD among patients with Type 2 diabetes (T2D) and its associated parameters in Bangladesh. A cross-sectional descriptive study design was chosen for data collection; data was collected from clinical laboratory test reports from A tertiary hospital in Bangladesh. The inclusion criteria were male and female patients from 30-90 years, diagnosed with type 2 diabetes mellitus. The data was analyzed using the SPSS version 26. Males show the highest prevalence of CKD in the age group of 51-60 (18.1%). The renal profile assessment revealed significant gender-based differences in several biochemical parameters, a higher percentage of males having abnormal levels compared to females in serum urea (p=0.02), creatinine (p=0.01), sodium plasma (p=0.05), and plasma bicarbonates (p= 0.001). The distribution of the estimated glomerular filtration rate showed that males had a higher representation in stages II (18.6%), suggesting delayed diagnosis. As CKD progressed, females appeared to catch up and surpass males in later stages, particularly Stage III (9.5%). This might suggest that they might have different risk factors that accelerate the progression of CKD. This study highlights that renal function declines with age. This study found substantial gender disparities in renal function among T2D patients, with males having a higher prevalence of aberrant renal parameters and more severe renal illness. These findings have significant implications for clinical care, indicating the need for genderspecific methods to preventing and treating renal problems.