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Identification of uropathogens and antimicrobial resistance of urinary tract infections at tertiary medical college in Bangladesh

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BRAC University

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Abstract

The goal of this study was to determine the frequency of different bacterial microorganisms and their antibiotic sensitivity in urine infections. Antimicrobial resistance has been steadily increasing for a number of years, reducing the effectiveness of antibiotics. Numerous factors, such as human behavior, can hasten the development of antibiotic resistance, drug impermeability, drug tolerance, drug destruction, and practices. The frequency, kinds, and antibiotic susceptibility of bacteria found in this investigation were urine sample investigations were conducted. 200 urine samples altogether, including both sexes and ages 0-90 years were examined in this investigation. These samples underwent analysis to look for the antibiotic vulnerability to pyogenic bacteria growing significantly. Organisms that are gram-positive accounted for 14% of the total, while Gram-negative microbes made for 86% which means gram-negative bacteria have a huge impact than Gram-positive bacteria in comparison. Enterococci spp, Staphylococcus aureus, Staphylococcus saprophyticus etc are examples of Gram-positive bacteria. On the other hand, Escherichia coli, Klebsiella spp, Acinetobacter spp, Pseudomonas spp etc are example of Gram-negative bacteria. The majority of the resistant Gram-positive bacteria susceptible to Nitrofurantoin but resistant in opposition to Ciprofloxacin. The majority of the resistant Gram-negative bacteria susceptible to Amikacin and Colistin but resistant in opposition to Azithromycin and Cefepime.

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This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Science in Microbiology, 2024.
Catalogued from PDF version of thesis.
Includes bibliographical references (pages 45-47).

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Thesis