Molecules associated with the development of lung cancer

Abstract

Molecular association with lung cancer is one of the most important and a very primary queries to understand the molecular basis of lung cancer and its development mechanism. There are different factors involved with the development of lung carcinoma. Smoking, environmental hazards, and occupational hazards are the main risk factors. Different molecules are involved differently in the development, progression, and spread of lung cancer. Similarly, some molecular associations are also found in the diagnosis and treatment of this disease. Epigenetic alterations have been reported widely in the sector of lung cancer which plays a major role in the genesis of lung cancer. Here in this review, we try to provide an overview of different molecular associations with lung cancer in different steps including- risk factors, disease induction, disease catalyzation, disease sustenance, epigenetic factors, biomarker appearance, and therapeutic purposes. We give more emphasis on different mutational changes which induce, accelerate and animate this deadliest disease. Our focus is also on different therapeutic aspects of lung cancer.