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Efficacy of CRISPR-Cas9 in treatment of HIV-AIDS

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bracu.type.groupStudent Works
dc.contributor.advisorNaser, Iftekhar Bin
dc.contributor.authorIbnat, Anika
dc.contributor.departmentDepartment of Mathematics and Natural Sciences
dc.date.accessioned2025-06-26T07:58:35Z
dc.date.available2025-06-26T07:58:35Z
dc.date.copyright2023
dc.date.issued2023-11
dc.descriptionThis thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Science in Biotechnology, 2023.en_US
dc.descriptionCatalogued from PDF version of thesis.
dc.descriptionIncludes bibliographical references (pages 41-42).
dc.description.abstractAIDS is a lethal viral infection that kills more than thousands of individuals every year as it spreads the virus via various modes of transmission. The modern era of biological research is exploring genome editing as a potentially effective way to prevent, treat and cure myriads of diseases with a novel genome engineering tool called CRISPR-Cas system which is now being studied worldwide as an attempt to treat and cure HIV-AIDS. Investigations have been carried from multiple research perspectives- from attempts to inhibit viral replication directly, preventing viral integration into host genome and disrupting specific cell-receptor coding genes in host to excision of provirus in latently infected cells in-vivo. Data collected from these investigations suggest potential of successful treatment of the disease. The limitations faced in the experimental protocols and results along with the gaps can be utilized as new focus of research investigation in this area.en_US
dc.description.degreeBachelor of Science in Biotechnology
dc.description.statementofresponsibilityAnika Ibnat
dc.format.extent52 pages
dc.identifier.otherID 16336012
dc.identifier.urihttp://hdl.handle.net/10361/26414
dc.language.isoenen_US
dc.publisherBRAC Universityen_US
dc.rightsBRAC University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission.
dc.subjectHIVen_US
dc.subjectAIDSen_US
dc.subjectGenome editingen_US
dc.subjectCRISPR-Casen_US
dc.subjectgRNAen_US
dc.subject.lcshAIDS (Disease)--Treatment.
dc.subject.lcshHIV infections--Treatment.
dc.titleEfficacy of CRISPR-Cas9 in treatment of HIV-AIDSen_US
dc.typeThesisen_US

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Thesis (Bachelor of Science in Biotechnology)