Antibiotic resistance pattern of Escherichia coli isolated from patients with urinary tract infection

Abstract

Urinary tract infections are considered as the second most common type of infection occurred in body. Escherichia coli is the most common cause of urinary tract of infection for both male and female, higher percentage found in female. This study ―Antibiotic Resistance Pattern of Escherichia coli Isolated from Patients with Urinary Tract Infection‖ was done with aim of surveying the amount of resistance among strain of Escherichia coli. In this present study, 300 E. coli samples were collected from patients with urinary tract infections from which 70% were female and 30% were male. These positive 300 samples of Escherichia coli were then taken for the antibiotic susceptibility testing which was performed using Kirby-Bauer disk diffusion method. Macrolides, beta lactam and quinolone group showed most of resistance with Azithromycin 78%, Cetfazidime 63%, ceftriaxone and cefuroxime 59%, Nalidixic acid 69%, Ciprofloxacin 55% and Levofloxacin 52%. From other groups, Cotrimoxazole showed 67% resistance. Aminoglycoside group showed less resistance with Amikacin 6%, Netilmicin 9%, tobramycin 15% and gentamicin 12%.From other groups less resistance showed with Meropenem 6%, Nitrofurantoin 17% and Colistin 20%.Besides that, patients resistant to multi-drug was 89.33% .This study showed increased resistance to antibiotics in Escherichia coli that is a serious warning to the treatment of infections caused by this bacterium in the region. Therefore, in order to prevent increased resistance to other antibiotics, it is essential to withhold prescriptions and unessential use of available antibiotics.