Factors associated with antifungal resistance and the recent development in detection & treatment: a review

Abstract

Antifungal resistance has become a growing concern in recent years, as it has become increasingly difficult to treat fungal infections due to the emergence of drug-resistant organisms. The prevalence of antifungal resistance can be analyzed through various factors, including environmental factors, evolutionary factors, and drug misuse. Environmental factors such as climate change and pollution can affect fungi's growth and survival, leading to resistant strains' development. Evolutionary factors such as genetic mutations and natural selection can also contribute to the emergence of drug-resistant organisms. Additionally, drug misuse, such as overuse or improper use of antifungal medications, can promote the development of resistance. Early detection of antifungal resistance is crucial for effective treatment, and various methods such as susceptibility testing and molecular diagnostics are available for this purpose. In conclusion, the prevalence of antifungal resistance is a complex issue that requires a multifaceted approach to address the various factors contributing to its emergence.