dc.contributor.author | Dash, Pritesh Ranjan | |
dc.contributor.author | Sheikh, Zara | |
dc.date.accessioned | 2016-12-03T18:13:56Z | |
dc.date.available | 2016-12-03T18:13:56Z | |
dc.date.issued | 2015 | |
dc.identifier.citation | Dash P.R, Sheikh Z (2015). Preliminary studies on phytochemicals and cytotoxic activity of methanolic rhizome extract of Hedychium coronarium. Journal of Pharmacognosy and Phytochemistry, 4(1): 136-139. | en_US |
dc.identifier.issn | 2278-4136 | |
dc.identifier.uri | http://hdl.handle.net/10361/7086 | |
dc.description | This article was published in the Journal of Pharmacognosy and Phytochemistry [©2015 Journal of Pharmacognosy and Phytochemistry] The definite version is available at: https://goo.gl/aChrRS | |
dc.description.abstract | The methanolic extract of the rhizome of Hedychium coronarium (Family- Zingiberaceae) was screened
for the presence of various phytochemicals by standard procedures and the cytotoxic activity was
evaluated by brine shrimp lethality bioassay. The present study indicates that the rhizome contain
carbohydrates, flavonoids, saponins, steroids and alkaloids. In brine shrimp lethality bioassay, the extract
showed potent cytotoxic action. The degree of lethality was found to be directly proportional to the
concentration of the extract ranging from the lowest concentration (1.25 μg/ml) to the highest
concentration (320 μg/ml). The LC50 value of the methanolic rhizome extract was 0.39 μg/ml, whereas
the LC50 of the reference anticancer drug vincristine sulphate was 0.52 μg/ml. | en_US |
dc.language.iso | en | en_US |
dc.publisher | © 2015 Journal of Pharmacognosy and Phytochemistry | en_US |
dc.relation.uri | https://goo.gl/aChrRS | |
dc.subject | Hedychium coronarium | en_US |
dc.subject | Cytotoxicity | en_US |
dc.subject | Brine shrimp | en_US |
dc.subject | Artemia salina | en_US |
dc.title | Preliminary studies on phytochemicals and cytotoxic activity of methanolic rhizome extract of Hedychium coronarium | en_US |
dc.type | Article | en_US |
dc.description.version | Published | |
dc.contributor.department | Department of Pharmacy, BRAC University | |