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To control site-specific skin gene expression, autocrine mimics paracrine canonical Wnt signaling and Is activated ectopically in skin disease

Kim, Dongwon; M. Zulfiquer Hossain; Nieves, Ashley; Gu, Lihong; Ratliff, Tabetha S.; Oh, Seung Mi; Park, Angela; Han, Seunghyun; Yang, Nicole B.; Qi, Ji; Taube, Janis M.; Kang, Sewon; Garza, Luis A.

Despite similar components, the heterogeneity of skin characteristics across the human body is enormous. It is classically believed that site-specific fibroblasts in the dermis control postnatal skin identity by modulating ...