School of Pharmacy (PHR): Recent submissions
Now showing items 41-60 of 628
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Nanotechnology advancement in the field of curing cancer
(BRAC University, 2022-11)The ability to treat sickness is continually evolving. In this field, various approaches are being used. One of the deadliest diseases for which there are now no better treatments is cancer. There is a lot of utilization ... -
Association of SIRT6 with obesity and diabetes
(BRAC University, 2022-11)SIRT6 is one of the sirtuin family members, a kind of NAD+-dependent histone deacetylase and ADP-ribose transferase enzyme. It controls aging, cancer, obesity, insulin resistance, inflammation, and energy metabolism, ... -
Safety and efficacy of dutasteride for male Androgenetic Alopecia
(Brac University, 2022-11)Background: One of the primary causes of male pattern baldness is thought to be the conversion of testosterone to dihydrotestosterone. Dutasteride, a dual 5-alpha-reductase inhibitor, can prevent this conversion from ... -
Impact of lifestyle on vitamin D deficiency during pregnancy: a literature review
(Brac University, 2023-02)Vitamin D is essential for fetal growth and maternal health, and vitamin D deficiency during pregnancy can lead to various health issues, such as preeclampsia, gestational diabetes and preterm birth in mothers and low birth ... -
A review on relationship of SNP at rs2228570 of VDR gene and different diseases in different populations
(Brac University, 2023-02)Multiple disorders are caused by mutations in the vitamin D receptor (VDR) gene. The VDR gene directs the body to manufacture vitamin D receptor protein (VDR). This vitamin D receptor is engaged in vitamin D-mediated ... -
A review of Isotretinoin and its association in affective disorder
(Brac University, 2023-03)Isotretinoin is a medication used in the treatment of severe to moderate acne. However, several studies have reported a potential association between Isotretinoin use and affective disorders (depression, anxiety, suicidal ... -
Music therapy as a potential treatment approach for the patients with ASD: a systematic review
(Brac University, 2023-07)Autism spectrum disorder is a neuronal developmental disorder which is commonly established in the early age of life and persist throughout the lifespan. Currently, there are very little option of pharmacological therapies ... -
In vitro biological screening of ethanol extract of Pterocarpus Indicus Willd. (Fabaceae) leaves
(Brac University, 2023-02)This research was carried out to assess the biological properties of the Pterocarpus Indicus Willd. leaves of the Fabaceae family. To study the leaves, antioxidant activity was examined using DPPH free radical scavenging ... -
Nanomaterials for diagnosis and treatment of brain cancer
(Brac University, 2023-03)Nanomaterials have shown significant promise in the diagnosis and treatment of brain cancer. These materials, because of their distinct physical and chemical properties, can be engineered to target specific molecules and ... -
A pharmacovigilance study on Memantine: signal detection of Rhabdomyolysis and death
(Brac University, 2023-02)Alzheimer's Disease (AD) is a complex and common neurological disorder and dementia's leading cause. Memantine works to treat moderate to severe AD. This study focused on Food and Drug Administration Adverse Event Reporting ... -
Investigation of in vitro antioxidant and cytotoxic properties of Lagerstroemia thorelli leaf extract
(Brac University, 2023-09)Lagerstroemia thorelli belongs to the Lythraceae family and is natively known as choto jarul. This study was undertaken to identify the antioxidant and cytotoxic properties of this plant since no previous reports on its ... -
Oral terbinafine-, fluconazole-, ravuconazole-, oteseconazole-induced hepatotoxicity and acute kidney injury in the treatment of onychomycosis: a pharmacovigilance study
(Brac University, 2023-02)Onychomycosis is a fungal infection in the nails. Oral antifungal therapies of onychomycosis; terbinafine, fluconazole, ravuconazole, otesaconazole may cause liver and acute kidney injury (AKI). This project aims to identify ... -
Bacteriophage therapy against nosocomial infection and airborne Infection control in ICU
(Brac University, 2023-02)The spread of antibiotic resistant nosocomial infections and cross transmission of airborne nosocomial infection have urged the scientific community to hunt for prevention and alternative treatments of it. This study aimed ... -
Screening of anthelmintic and insecticidal activity of Flacourtia jangomas fruit pulp
(Brac University, 2023-02)The study aimed to evaluate the anthelmintic and insecticidal activity of Flacourtia jangomas fruit pulp (MFJ). The plant's anthelmintic property was tested on Pheretima posthuma (Earthworm), while its insecticidal ... -
A review on the role of SNP at rs1544410 of VDR gene in different diseases
(Brac University, 2023-02)Single nucleotide polymorphism (SNP) can take place in the vitamin D receptor (VDR) gene which can cause alteration in normal procedure of the VDR. Thus, ultimately restricting the work of vitamin D which can be a precursor ... -
Evaluation of anti-microbial activity and minimum inhibitory concentration of Flacourtia jangomas fruits
(Brac University, 2023-02)The objective of this study was to determine the particular antibacterial components of Flacourtia jangomas fruit. The antimicrobial screening used the Kirby-Baurer disk diffusion technique and the Broth dilution method, ... -
Efficacy analysis and prediction in phase II clinical trials of non-small cell Lung Cancer
(Brac University, 2023-03)The American Cancer Society estimates that lung cancer is the most common type of cancer and nearly 25% cancer deaths result from lung cancer, of which three subtypes account for 80% of cases. This is the rationale behind ... -
Study of viral load reduction in disposable face masks upon UV-C exposure using RT-qPCR
(Brac University, 2022-10)This research is designed to promote the long-term usage of surgical masks, proper disposal, environmental protection, controlled production and the developed UV-C chambers validation. Moreover, we sought to evaluate the ... -
A review on association of mothers’ single Nucleotide Polymorphism (BsmI) of vitamin D receptor gene with risk of preterm birth and low birth weight
(Brac University, 2023-09)Preterm birth and low birth weight are linked to increased neonatal morbidity and mortality and can harm a child's health and development. An expanding corpus of research confirms that a number of genetic and immunological ... -
In-vitro biological screening of ethanol extract of Lagerstroemia thorelli leaves
(Brac University, 2023-02)The research on Lagerstroemia thorelli was performed for evaluating potential medicinal properties of the plant. In order to accomplish this goal, several experiments like antimicrobial property test which included bacterial ...