School of Pharmacy (PHR): Recent submissions
Now showing items 41-60 of 693
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Targeting DHFR in breast cancer: exploring expression patterns and identifying potential inhibitors through docking studies
(Brac University, 2024-03)Dihydrofolate Reductase (DHFR) is a critical enzyme linked to tumor development in various cancers, including breast cancer. Breast cancer, a prevalent cancer diagnosed in approximately 2.3 million people each year, arises ... -
A review on association of mothers’ Vitamin D deficiency and single nucleotide polymorphism of Vitamin D receptor gene (ApaI) with risk of preterm birth and low birth weight
(Brac University, 2023-09)Preterm birth and low birth weight are significant public health concerns associated with adverse neonatal outcomes and long-term health implications. Preterm birth is the leading cause of death in infants under the age ... -
Nanobubble drug delivery system
(Brac University, 2023-05)Ultrasound guided drug delivery has become the focus of increasing the possibilities of improving therapeutic treatments. This technique has been used in various combinations along with micron size water filled gas ... -
A comparative analysis of attention abilities in post-covid and non-covid patients using Ace-III scale
(Brac University, 2024-05)This study investigates the impact of COVID-19 on attention skills among patients. Using a comparative cross-sectional design, attention scores from the ACE-III questionnaire were analyzed in post COVID-positive and ... -
A study on antibiotic resistance pattern among patients of a selected hospital in Narayanganj, Bangladesh
(Brac University, 2024-04)The emergence and spread of multi-drug-resistant (MDR) pathogens pose a significant threat to global public health, challenging the efficacy of antimicrobial treatments and leading to increased morbidity, mortality, and ... -
Pooled analysis of response rate and overall survival of Tyrosine Kinase inhibitor combinations in phase II clinical trials of non-small cell lung cancer
(Brac University, 2023-10)Lung cancer is a prominent cause of death annually. It is the most common cancer worldwide and the leading cause of cancer deaths in men and women. In this research, we focused mostly on non-small cell lung cancer (NSCLC) ... -
Antioxidant and hypoglycemic effect of Nypa Fruticans wurmb fruit shell
(Brac University, 2024-01)Plant extract-based natural medicines are becoming more and more popular as a substitute for synthetic drugs, which raises safety concerns. This study examined Nypa fruticans's hypoglycemic and antioxidant impact. We ... -
Role of circular RNA in neurological disease
(Brac University, 2023-07)Neurological disorders are increasingly recognized as major causes of death and disability worldwide. Among different types of treatment options, circRNAs might play vital roles in Alzheimer’s disease, Parkinson’s disease, ... -
Assessing therapeutic safety and efficacy of Pazopanib, Pembrolizumab plus Axitinib and Nivolumab plus Ipilimumab in Renal Cell Carcinoma: a systematic review and meta-analysis
(Brac University, 2023-11)Renal cell carcinoma (RCC) is the predominant form of kidney cancer. It is a highly prevalent form of solid tumor, and the limited availability of accurate disease models has impeded progress in the field of human kidney ... -
Comparative efficacy of Sorafenib, and Lenvatinib in Hepatocellular Carcinoma: a meta-analysis
(Brac University, 2023-11)Hepatocellular carcinoma (HCC) is an important healthcare problem with developing therapeutic options. This meta-analysis evaluates the effectiveness and safety of lenvatinib and sorafenib, focusing largely on overall ... -
A review on the use of Ganaxolone in the treatment of Epilepsy
(Brac University, 2024-03)Epilepsy currently affects about 50 million people and approximately 10% of the population will have at least one seizure during their lifetime yet very little is known about this condition. This condition can occur as a ... -
Computational insights into molecular docking strategies for non-small cell lung cancer drug discovery
(Brac University, 2024-02)This work addresses computational approaches to non-small cell lung cancer (NSCLC) drug discovery, highlighting the vital part that molecular docking plays in the early stages of drug discovery. It demonstrates the ... -
A review on Metastatic Melanoma combination therapy Ipilimumab-Nivolumab
(Brac University, 2023-10)Chemotherapy, radiation therapy, surgery, and other treatments have proven to be ineffective for a patient suffering with metastatic melanoma. Recently, immunotherapy has become a potential method for treating the condition. ... -
Use of stem cells for the Study and treatment of type 1 diabetes
(Brac University, 2023-12)Diabetes mellitus (DM) is a significant and prevalent chronic disease with high rates of morbidity and death. The loss of pancreatic cells characterizes type 1 diabetes mellitus (T1DM), For this reason, the body lacks ... -
Parkinson's disease in Bangladesh: An evaluation of the public knowledge and awareness
(Brac University, 2021-09)Background: Parkinson’s Disease poses a monumental health burden, one which is often misunderstood and underestimated by the general public. Objective: This study was designed to assess Bangladesh’s general population’s ... -
Risk of cancer associated with antihypertensive drugs
(Brac University, 2022-07)Antihypertensive medications are commonly used to treat hypertension, heart failure, and, more recently, cardiovascular risk reduction. Antihypertensive medicines have been implicated in the control of cell proliferation, ... -
A review on phytochemistry and pharmacological activity of asparagus racemosus
(Brac University, 2020-12)Medicinal plants play a significant role in formulation of medications. Asparagus racemosus is one of the ancient medicinal plants with a lot of therapeutic values. This is a traditional medicinal plant belongs to the ... -
A study of glioblastoma gene profile
(Brac University, 2020-01)Glioblastoma is one of the most common and deadliest forms of brain cancer. The cell growth rate of glioblastoma is highly proliferated and they travel into other cells. Glioblastoma multiform introduced in 1926 by ... -
Concomitant use of multiple antipsychotics to treat Schizophrenia: Risk benefit analysis
(Brac University, 2022-06)This article discusses about what schizophrenia and its symptoms are and what antipsychotics can be used to treat the disease. The main cause of schizophrenia is not found and some hypothesis and pathways for the disease ... -
Comparison and evaluation of aceclofenac nanoemulsion formulation using homogenization and ultrasonication techniques
(Brac University, 2020-02)The goal of this study is to evaluate aceclofenac nanoemulsion formulations with varying surfactant-co-surfactant ratio and method of preparation. Aceclofenac is a BCS class II NSAID, with greater anti-inflammatory ...
