School of Pharmacy (PHR): Recent submissions
Now showing items 21-40 of 628
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A review on relationship of SNP at rs7975232 (ApaI) of VDR gene and different diseases in different population
(Brac University, 2023-08)A variety of health conditions arise from changes in the gene responsible for the vitamin D receptor (VDR). This gene provides instructions for making a protein called the vitamin D receptor, which is important for how ... -
A review on the potential of repurposing of metformin for colon cancer and breast cancer
(BRAC University, 2023-02)Metformin, a hypoglycemic agent is currently being repurposed for the treatment of different types of cancer due to its pleiotropic functions, affordability, stability at room temperature with long shelf life, broadly ... -
A review on the role of artificial intelligence in healthcare transformation
(Brac University, 2022-10)Artificial intelligence (AI) is an influential area of computational science which can significantly transform medical practice and healthcare delivery. There are many cases where AI can conduct healthcare tasks better ... -
Signal detection of Rhabdomyolysis and death for galantamine: a pharmacovigilance study
(Brac University, 2023-02)Galantamine is one of the common acetylcholinesterase inhibitors used to treat Alzheimer's disease, a neurodegenerative disorder. This study was conducted to determine the impact of galantamine on mortality rate and ... -
Review on simultaneous estimation of fixed dose combinations (FDC): system suitability testing (SST) parameters of RP-HPLC analysis
(Brac University, 2022-12)This study presents the system suitability criteria for the assessment of multiple fixed dose combinations using reversed - phase chromatography. RP-HPLC is a separation technique based on the lipophilic interaction ... -
A comprehensive review on drug repurposing in cancer treatment
(Brac University, 2023-08)Cancer, a complex and highly detrimental group of medical conditions, continues to become a significant global health burden. Despite oncology research's advances, cancer drug development has fallen behind due to a number ... -
An in-silico based multi epitope vaccine construction of flagellin protein opposing Helicobacter Pylori bacteria (H. Pylori)
(Brac University, 2024-02)Helicobacter pylori (H. pylori) bacteria is a gram-negative bacteria that has capability to cause serious disease in human stomach by leading into peptic ulcer, mucosal lymph tissue, stomach cancer. According to WHO, it ... -
A review on Bruton's Tyrosine Kinase inhibitors to outline the scopes of further advancements in the treatment of cancer
(Brac University, 2023)In many B cell malignancies, Bruton's tyrosine kinase (BTK), a non-receptor kinase, plays a significant role in oncogenic signaling that is essential for the proliferation and survival of leukemic cells. BTK works as a ... -
In-silico vaccine construction: targeting HPV major capsid L1 protein
(Brac University, 2024-02)Cervical cancer is a prevalent outcome of human papillomavirus (HPV) infection, which continues to be a major global health concern. Utilizing virus-like particles (VLPs) based on L1 proteins is one of the methods used to ... -
A review on the recent advancements on nanoparticles drug delivery approaches in anti-cancer treatment
(Brac University, 2023-03)Nanoparticle drug delivery systems show a more promising approach and convenient treatment than conventional therapy to treat cancer. A broad range of nanoparticles, including as Inorganic Nanoparticle, Liposomes Nanoparticle, ... -
PCSK9i: proprotein convertase subtilisin/kexin type 9 inhibitor a new phase of lipid-lowering treatment
(Brac University, 2023-02)One of the largest global causes of morbidity and mortality is cardiovascular disease (CVD). Elevated low-density lipoprotein (LDL) levels and adverse cardiovascular outcomes are linked to increased levels of the proprotein ... -
Comparing effectiveness and safety of combination therapy for esophageal and gastro esophageal junction cancer: a comprehensive meta-analysis
(Brac University, 2023-12)Introduction: In cases of resectable esophageal cancer, neoadjuvant immune checkpoint inhibitors and chemotherapy have been examined. Nonetheless, conflicting findings have been found in subsequent research. Thus, meta-analysis ... -
Targeting BRAFV600E in the treatment of CRC
(Brac University, 2023-10)The increasing prevalence of BRAFV600E mutated cancers has led to the search and development of targeted therapies against BRAF mutation. Multiple cancers, including colorectal cancer (CRC), have been linked to this ... -
In vitro biological screening of ethanol extract of Pterocarpus Indicus Willd. (Fabaceae) leaves
(Brac University, 2023-04)This research was carried out to determine the biological properties (cytotoxic, antimicrobial) of a medicinal plant, named Pterocarpus Indicus Willd, which belongs to Fabaceae family. For evaluating cytotoxic property ... -
Parameters of clozapine treatment in patients with treatment-resistant Schizophrenia
(Brac University, 2022-11)Treatment-resistant schizophrenia (TRS) is familiar to one in three schizophrenia patient and clozapine is referred as only drug which has the approval for the remedy of TRS. After identifying TRS, clozapine treatment ... -
Identifying for risk of psychological disorder in COVID-19 survivors of Bangladesh
(BRAC University, 2022-12)The psychological problem increased significantly during the pandemic of Corona virus. In this research, a significant relationship between psychological disease and the effect of Coronavirus has been tried to correlate. ... -
A review on genotoxicity of different drug molecule
(BRAC University, 2022-11)In the field of genetics, genotoxicity is a property of chemical compounds that results in mutations by harming a cell’s genetic material. In genetics, it’s also used to define a harmful reaction on a cell’s genetic substance ... -
A review on classes of anti diabetic drugs and synthetic methods to access them: classical and modern approaches
(Brac University, 2023-02)Diabetes mellitus (DM) is a global health problem that threatens and hurts a lot of people every year. Most people with diabetes have type 2 diabetes, and diabetic care relies heavily on oral anti-diabetic medication. Oral ... -
Antimicrobial peptides in the treatment of dermatosis
(Brac University, 2023-02)Dermatosis refers to any skin defect or lesion on the skin due to scratches, wounds, ulcer, sunburn, skin abnormalities, skin thinning, different extrinsic and intrinsic factors and results allergy, skin infection, ... -
Research on measuring the capacity of a UV-disinfectant machine by disinfecting masks used by Covid-19 infected patients
(Brac University, 2022-10)The present study aims to measure an ultraviolet type C compartment’s disinfection capacity of mask used by covid-19 patients through biochemical testing. The sample was taken from covid-19 positive patients and stored in ...