School of Pharmacy (PHR): Recent submissions
Now showing items 1-20 of 628
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Frequent dengue outbreaks in South Asian countries: analysis of associated risk factors and possible preventive measures
(Brac University, 2024-02)Dengue, a mosquito borne viral disease has now become one of the most alarming threats of the world. Each year approximately 400 million people are affected by dengue globally. Among them 100 million people get sick by the ... -
An examination of therapeutic synergy: a comprehensive meta-analysis comparing the efficacy of TAS-102 and FOLFOX as a combination therapy for colon cancer
(Brac University, 2024-02)The treatment of colon cancer is a major healthcare issue that requires exploration of several treatment approaches. With an emphasis on overall survival, progression-free survival, and adverse events, this meta-analysis ... -
Occurrence of analytical techniques recommended by B.P. for certain formulation
(Brac University, 2023-05)This study reviews the most common analytical methods that have been recommended in the B.P. 2013. We discuss the frequency of analytical methods that have been recommended in the monograph of BP 2013. This study also ... -
In silico design of a capsid vertex component 1 protein targeted multi-epitope vaccine against cytomegalovirus
(Brac University, 2024-02)Cytomegalovirus is a virus causing irreversible neurological damage in newborns. In this study, in silico computational method was performed where, as primary protein, Capsid Vertex Component 1 Protein of cytomegalovirus ... -
Assessment of CNS depressant activity of Nypa Fruticans Wurmb fruit pulp
(Brac University, 2024-02)Nypa fruticans Wurmb (Family: Arecaceae) or Nipa palm is locally known as “Golfol” in Bangladesh which is of great interest now for its multiple uses. The present investigation was carried out to evaluate the CNS depressant ... -
A review on potential anticancer properties of antidiabetic drugs: metformin and sulfonylureas
(Brac University, 2024-02)Diabetes mellitus is a public health emergency that is increasing drastically worldwide. In many research findings, it is shown that it causes not only cardiovascular diseases but also increases the risk of cancer. Metformin ... -
Clinical outcomes and safety comparison of gemcitabine plus cisplatin, capecitabine monotherapy, and gemcitabine plus oxaliplatin in the management of gallbladder carcinoma: a comprehensive meta-analysis
(Brac University, 2024-02)Introduction: The utilization of chemotherapy treatment (CT) in the context of biliary tract cancers (BTC) remains a subject of considerable debate. To date, no comprehensive efficacy assessment has been conducted to ... -
Efficacy analysis of tyrosine kinase inhibitor combinations in phase II clinical trials of non-small cell lung cancer
(Brac University, 2023-01)Research is required in the area of non-small cell lung cancer, due to its widespread prevalence. Efforts to enhance the accessibility, evaluative simplicity, and prediction accuracy of endpoints in clinical trials are ... -
A review on principles of molecular docking and its application in drug discovery
(Brac University, 2024-03)Molecular docking (MD) is a computational technique that provides structural information and binding affinity of protein-ligand complexes in its thermodynamically favored conformation. This aids researchers in identifying ... -
Drug repurposing: search for targeted drug candidates in the treatment of HER2 positive breast cancer
(Brac University, 2023-09)According to GLOBOCAN data, 2020, breast cancer (BC) is the leading cause of cancer-related mortalities worldwide, with HER2 positive breast cancer being very prevalent. The rising incidence of HER2 positive breast cancer ... -
Comparison of conventional doxorubicin with liposome encapsulated doxorubicin as a treatment of breast cancer-a review
(Brac University, 2023-07)Breast cancer continues to be one of the most common reasons for hospitalization and mortality each year. As time goes on, novel anticancer drug formulations are being released on the market, raising the concern of medical ... -
A review on combinatorial therapies in Melanoma
(Brac University, 2023-10)Melanoma is the most deadly form of skin cancer due to its resistance to traditional cytotoxic treatment. However, innovative treatments have changed this disease's clinical trajectory. Understanding cancer microenvironment ... -
Drug repurposing: potential of Antimicrobial Drugs in Breast Cancer Treatment
(Brac University, 2023-08)Researchers and doctors have been encouraged to repurpose currently used medications to lessen the financial burden of drug development and provide potential novel treatments because of the rising expense of drugs globally, ... -
Nanoparticle with microneedle-mediated drug delivery system
(Brac University, 2023-04)Microneedle-mediated drug delivery combined with nanoparticles is a promising approach that has garnered significant research interest in recent years. This review discusses the latest advances in this approach, exploring ... -
Frequency of analytical techniques recommended by British Pharmacopoeia (BP)
(Brac University, 2023-09)In this study, the most common assay type for the formulations in British Pharmacopoeia (BP. 2013 edition) monographs was determined. UV-vis spectroscopy, Reverse phase chromatography, Normal phase chromatography, Acid-base ... -
A collection of data on several formulations assay types and subtypes
(Brac University, 2023-09)This paper reviews a number of the British Pharmacopeia-approved drug analysis methods. A list was created by compiling the several assay types and subtypes that were performed for each formulation. Bar and pie charts were ... -
Effect Of sodium glucose co-transporter 2 inhibitors on weight reduction in overweight and obese population: A review
(Brac University, 2022-10)Obesity is a global health concern and a large percentage of world is affected by it. Lifestyle changes are necessary and several therapy options are available to address it. Sodium glucose cotransporter 2 (SGLT-2) ... -
RNA drugs and RNA targets for small molecules: Prospects and challenges
(Brac University, 2021-08)RNAs are the small molecules that have been inferred in many human diseases and they are important for gene regulation, gene expression, and cellular information transfer. The highly structured elements of the messenger ... -
Investigation of in-vitro antidiabetic and antioxidant properties of Lagerstroemia thorelli leaf extract
(Brac University, 2023-09)This study was aimed to assess antioxidant and antidiabetic properties of Lagerstroemia thorell since no previous reports on its bioactivity screening were found during extensive literature search. Antioxidant activity was ... -
A review on pharmacological activities of prenylated alkaloids isolated from nature
(Brac University, 2023-02)Nature is a vast source of resources and has provided us with an abundance of natural products with various functional attributes. Prenylated alkaloids provides additional functionalities to natural products, including ...