School of Pharmacy (PHR): Recent submissions
Now showing items 1-20 of 693
-
Review on RBC a natural model for avanced/ targeted drug delivery system for anti-cancer therapy: potential and challenges
(Brac University, 2022-04)Red blood cell loaded therapeutic agents have been acknowledged because of its advantageous biologic properties. Among all the drug carriers, red blood cell is being a unique nano drug carrier and so considered as a vascular ... -
Understanding COVID-19 vaccine development and impact
(Brac University, 2024-04)A global scientific initiative has been launched to produce viable vaccines against the SARS-CoV-2 virus in response to the COVID-19 pandemic. The review article offers a thorough investigation of few significant aspects ... -
Construction of vaccine against Herpes Zoster Virus Glycoprotein E using In-silico method
(Brac University, 2023-02)Herpes zoster virus is a member of Alphaherpesvirinae subfamily and genus Varicellovirus of herpesviridae. Herpes zoster virus or Shingles is a viral disease. Recently, people are more suffering due to this virus. The ... -
A review on role of anti-SARS-CoV-2 monoclonal antibodies in the treatment of COVID-19
(Brac University, 2022-02)Traditional treatments and symptomatic care are still the only options for most patients as no therapeutic drug has been licensed for treating COVID-19 yet. Monoclonal antibodies generated from convalescent patients or ... -
Pooled analysis of progression-free survival and overall survival in phase II clinical trials of breast cancer
(Brac University, 2024-05)Metastatic breast cancer requires more investigation because of its high incidence. Efforts to improve the accessibility, evaluative simplicity, and predictive accuracy of clinical trial endpoints are ongoing. In this ... -
In vivo antidiarrheal activity of Nypa fruticans wurmb fruit pulp
(Brac University, 2024-02)Nypa fruticans wurmb has long been utilized in traditional medicine to treat a variety of illnesses including diarrhea. The study was conducted to evaluate antidiarrheal property of the methanolic fruit pulp extract of N. ... -
Antimicrobial resistance pattern in different age groups - a retrospective study
(Brac University, 2024)According to WHO, antibiotic resistance has emerged as a serious public health risk in the 21st century. To highlight the situation of antibiotic resistance in Dhaka city, Bangladesh, a retrospective study was conducted ... -
A review on newly approved PARP inhibitors: Talazoparib and Olaparib
(Brac University, 2024-01)This review delves into the intricate landscape of Poly ADP-ribose polymerase (PARP) inhibitors, specifically focusing on two notable contenders in cancer therapy – Talazoparib and Olaparib. By targeting the DNA Damage ... -
A review on the rare diseases and subsequent orphan drugs
(Brac University, 2022-06)Worldwide among every existing disease, approximately 5000-8000 are often referred to as rare diseases due to their uncommon, chronic, progressive, degenerative, and life-threatening characteristics. This review specifically ... -
Trend in approval of targeted biologics in the last two decades
(Brac University, 2024-04)Over the past two decades, the approval of targeted biologics has significantly transformed therapeutic landscapes, particularly for chronic diseases like cancer. These therapies, specifically target diseases' molecular ... -
A review on bispecific antibody (blinatumomab) for the treatment of acute lymphoblastic leukemia
(Brac University, 2024-07)Acute lymphoblastic Leukemia has currently about 6,550 new cases from which about 3,590 are male and about 2,960 are females. ALL occurs in fewer than half of 1% of all cancer in the US. There are multiple subtypes of ... -
Bioinformatics analyses of key regulators of NF-κB pathway in relation with small cell lung carcinoma
(Brac University, 2024-07)Small cell lung cancer is the most aggressive form of cancer and its progression is very fast and quick. The NF-kB pathway and small cell lung cancer are connected to each other. Despite all the findings and the advanced ... -
A review on the teratogenic effects of isotretinoin
(Brac University, 2024-01)This review article presents recent studies on isotretinoin, a potent oral retinoid that is frequently recommended to treat severe acne but has been clearly associated with teratogenic effects when given to expectant ... -
In-silico based multiepitope vaccine construction of envelope glycoprotein against Hantavirus
(Brac University, 2024-04)Hantavirus is a zoonotic virus which is responsible for causing hemorrhagic fever with renal syndrome & hantavirus pulmonary syndrome. But still, there is no stable vaccine developed for this virus. Developing a multiepitope ... -
A review on the effect of Moringa oleifera in the treatment of hypertension
(Brac University, 2024-04)The multipurpose plant Moringa oleifera contains varieties of biologically active phytochemicals in different parts of the plant that show therapeutic effects on various diseases like diabetes, cancer, and hypertension ... -
A current insight into Aurora kinase inhibitors and their potential as anticancer agents
(Brac University, 2024-03)The Aurora kinases, comprising Aurora A, Aurora B, and Aurora C, constitute a family of serine/threonine protein kinases that plays a fundamental role in ensuring precise mitotic progression, regulating multiple phases of ... -
A review on association of genetic polymorphism with thyroid hormone level leading to different diseases
(Brac University, 2024-04)The study delved into the investigation of CYP27B1 hydroxylase, a vital enzyme responsible for converting 25-hydroxyvitamin D3 (25OHD3) into 1,25(OH)2D3, the most potent natural form of vitamin D crucial for immune modulation ... -
A review on antidiabetic property of mangrove plants
(Brac University, 2023-09)At present, diabetes mellitus encompasses an extensive number of metabolic disorders characterized by chronic hyperglycemia, representing a significant global health concern. According to the mangrove plant it has many ... -
A study on the side effects of Covid-19 vaccines in Bangladesh
(Brac University, 2022-04)Pfizer-BioNTech, Oxford-AstraZeneca, Sinopharm, and Moderna have all recently introduced vaccines to combat the COVID-19 pandemic in Bangladesh. These vaccines have been associated with mild-to-moderate adverse events ... -
Potential use of mesenchymal stem cells in regenerative medicines: a review
(Brac University, 2022-08)The utilization of Mesenchymal Stem Cells (MSCs) in biomedicine has expanded dramatically over the past 50 years. MSCs are a diverse group of cells, extracted from fat, synovium and bone marrow with the ability to ...
