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Emerging therapies of Alzheimer’s disease: a comprehensive review
(Brac University, 2022-11)
Alzheimer’s disease is a complex, debilitating neurodegenerative disorder, with a rapidly increasing worldwide prevalence. Despite decades of intense research, therapeutics for Alzheimer's disease are still limited to ...
Mutation in DNA polymerase γ: mitochondrial disorders
(Brac University, 2022)
Together with key components of the mitochondrial DNA (mtDNA) replication machinery,
DNA polymerase γ (POLG) replicates the human mitochondrial genome. Defects in mtDNA
replication or nucleotide metabolism result in mtDNA ...
Covid-19 vaccine for transdermal delivery: formulation consideration and microneedle accession
(Brac University, 2021-06)
Covid-19, a worldwide disease, affects millions of people. As of now, there is no effective technique to avoid infection. This outbreak emphasizes pandemic preparedness. Contrary to popular belief, the Covid-19 vaccination ...
Precision medicine in four deadliest Cancers of the world : present practices & future prospects
(Brac University, 2022-02)
Cancer is a very personalized disease which is why conventional oncology treatment following the ‘one size fits all’ method is unable to cure all patients effectively and for this, cancer remains one of the leading causes ...
A study on less explored plants with potential neuroprotective activity against neurodegenerative diseases
(Brac University, 2020-12)
The gradual deterioration of the structure and function of neurons, including neural death, is known as neurodegeneration. The most known diseases of neurodegeneration are Alzheimer’s, Parkinson's, Huntington's, Amyotrophic ...
Immuno-informatics aided -design of multi-epitope based vaccine against Nipah henipavirus Glycoprotein G.
(Brac University, 2021)
In the family Paramyxoviridae, the genome of Nipah henipavirus belongs. The Henipa virus is a descendant of the Hendra and Nipah viruses. The most recent Nipah henipavirus outbreak in Kerala occurred in 2018 in the Kozhikode ...
An in silico Method to developing an epitope-based peptide vaccination against SARS-CoV-2's Envelope Protein (E)
(Brac University, 2022-06)
The new coronavirus (SARS-CoV-2) pandemic, which has killed millions of people throughout
the world, has afflicted millions of people. SARS-CoV-2 therapies were severely limited due to
the virus's quick pathogenicity. ...
Use of nano-emulsion for delivery of NSAID
(Brac University, 2021-02)
This review article manifest Non-steroidal anti-inflammatory drug (NSAID) drug delivery system based on nano-emulsified carriers. The main target is to find out a suitable nano-emulsion technique using different types of ...
Immunological biomarkers in autism: a review
(Brac University, 2020-12)
Autism spectrum disorder (ASD) is a specific heterogenous neurodevelopmental disorder focused on the occurrence and intensity of core anomalies in social contact and repetitive behaviour, with complex pathogenesis and ...
Harnessing exosomes as a drug delivery system for neurodegenerative diseases
(Brac University, 2021-08)
Exosomes are recently discovered bilayer containing membrane which are small-sized (30-
100mm) nanovesicles that are formed due to the fusion of multivesicular bodies with the
plasma membrane. Exosomes are involved in ...