Search
Now showing items 21-30 of 126
Recent advancement of biologics in Asthma
(Brac University, 2022-03)
It is quite visible that in the comparison to the patients having well-controlled asthma, patients having severe uncontrolled asthma do have disproportionately high rate of morbidity and also health-care usage. Whereas the ...
Antidiabetic properties of Moringa oleifera: a review
(Brac University, 2022-11)
Diabetes mellitus is a metabolic disorder that affects people all over the world. Currently, drugs made from herbs are used as medicinal plants which can treat a wide range of illnesses. Besides, plant-derived drugs improve ...
Dendritic cell vaccine for the treatment of cancer
(Brac University, 2022-02)
Dendritic cells (DCs) serve as sentinels for the immune system, antigen-specific immune
responses are initiated and regulated. Cross-priming, a mechanism in which DCs activate CD8
T cells by presenting external antigens ...
Targeting circular RNA for cardiovascular diseases
(Brac University, 2022-11)
Circular RNAs (CircRNAs) are ubiquitous, and covalently closed loop structures. They are single-stranded molecules without free 3′ and 5 ′ ends. CircRNAs have been rapidly gaining momentum as a potential therapy option for ...
Antimicrobial peptides in skin diseases
(Brac University, 2022-03)
Skin diseases, including inflammatory and infections, result from disruptions in the skin's
barrier. Antimicrobial peptides (AMPs) have recently gained attention as potential treatments
for inflammatory, soft skin tissue ...
Screening of anthelmintic activity of Heritiera fomes
(Brac University, 2022-03)
Heritiera fomes is a mangrove medicinal plant which is rich of ethnomedicinal usage against
helminths. At present, it is found that H. fomes is a good reservoir of compounds such as
phenols, tannin, alkaloids which have ...
Emerging therapies of Alzheimer’s disease: a comprehensive review
(Brac University, 2022-11)
Alzheimer’s disease is a complex, debilitating neurodegenerative disorder, with a rapidly increasing worldwide prevalence. Despite decades of intense research, therapeutics for Alzheimer's disease are still limited to ...
Mutation in DNA polymerase γ: mitochondrial disorders
(Brac University, 2022)
Together with key components of the mitochondrial DNA (mtDNA) replication machinery,
DNA polymerase γ (POLG) replicates the human mitochondrial genome. Defects in mtDNA
replication or nucleotide metabolism result in mtDNA ...
Precision medicine in four deadliest Cancers of the world : present practices & future prospects
(Brac University, 2022-02)
Cancer is a very personalized disease which is why conventional oncology treatment following the ‘one size fits all’ method is unable to cure all patients effectively and for this, cancer remains one of the leading causes ...
An in silico Method to developing an epitope-based peptide vaccination against SARS-CoV-2's Envelope Protein (E)
(Brac University, 2022-06)
The new coronavirus (SARS-CoV-2) pandemic, which has killed millions of people throughout
the world, has afflicted millions of people. SARS-CoV-2 therapies were severely limited due to
the virus's quick pathogenicity. ...