Browsing School of Pharmacy (PHR) by Title
Now showing items 524-543 of 607
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Role of toll-like receptors in cancer immunotherapy– a review
(Brac University, 2021-08)Cancer is recognized as the major concern in today’s world. It is a condition or a group of diseases in which cells are abnormally divided. In the past century, the understanding and treatment of cancer has developed a lot ... -
Role of voltage-gated sodium channel modulators in peripheral nervous system disorders
(Brac University, 2022-02)In current therapy for controlling peripheral nervous system disorders, one of the milestones is the voltage-gated sodium channel modulators. They have higher efficacy with improved side effects. They target the channel ... -
Safety and efficacy of cisplatin combinations with vinorelbine, paclitaxel and gemcitabine – a systematic review and meta-analysis
(Brac University, 2023-06)Introduction: The aim of the study is to assess the efficacy of cisplatin combinations with paclitaxel, gemcitabine and vinorelbine for the first line treatment of non-small cell lung cancer.Methods: The Cochrane library, ... -
Safety and efficacy of dutasteride for male Androgenetic Alopecia
(Brac University, 2022-11)Background: One of the primary causes of male pattern baldness is thought to be the conversion of testosterone to dihydrotestosterone. Dutasteride, a dual 5-alpha-reductase inhibitor, can prevent this conversion from ... -
Safety and efficacy of Ibuprofen in children: A review
(Brac University, 2022-09)This study aims to compile data from numerous recent investigations on the pharmacological characteristics, therapeutic applications, and safety of ibuprofen. Ibuprofen is frequently used to treat fever, discomfort, ... -
Screening of anthelmintic activity of Heritiera fomes
(Brac University, 2022-03)Heritiera fomes is a mangrove medicinal plant which is rich of ethnomedicinal usage against helminths. At present, it is found that H. fomes is a good reservoir of compounds such as phenols, tannin, alkaloids which have ... -
Screening of anthelmintic and insecticidal activity of Flacourtia jangomas fruit pulp
(Brac University, 2023-02)The study aimed to evaluate the anthelmintic and insecticidal activity of Flacourtia jangomas fruit pulp (MFJ). The plant's anthelmintic property was tested on Pheretima posthuma (Earthworm), while its insecticidal ... -
Screening of hypoglycemic effect and antioxidant potential of trewia nudilfora leaf extracts
(BRAC University, 2015-08)Diabetes is one of the most alarming diseases of the current civilization, especially due to its life-long dragging condition and increasing number of patients. In the thirst of combating such circumstances there relies a ... -
Sea snail venom: A potential alternative to Opioid Analgesics
(Brac University, 2021-04)The marine environment is a large and complex source for novel medicines. Conopeptides are present in sea snail venoms that have been detected to block pain by activating a separate molecular mechanism exploited by opioid ... -
Self-micro emulsifying drug delivery system: An approach to improve the solubility of Itraconazole
(Brac University, 2022-09)The study is designed to improve the bioavailability of Itraconazole by developing a self-micro emulsifying drug delivery system (SMEDDS). A series of SMEDDS were prepared with different ratios of oil, surfactant and ... -
A short review on additional therapeutic effects and adverse effects of sedative and hypnotic drugs
(Brac University, 2020-01)This study was conducted to list down the adverse effects and additional therapeutic effects of sedative hypnotic drugs through reviewed articles. There are different kinds of drugs as sedative hypnotic. Benzodiazepine and ... -
A short review on novel anti-malarial Heterocyclic aromatic therapeutic agents: synthesis, efficacy and effectiveness of potential drug candidates for malaria
(Brac University, 2019-04)Malaria, a vector-borne parasitic tropical illness has exponentially become a major disease as well as life threatening if not treated with right medication. Elimination of malaria is firmly back as a mainstream policy but ... -
A short review on the phenotypic, genotypic and immunological developments for Zika virus
(BRAC University, 2018-09)Zika Virus (ZIKV) has recently received much attention right after the outbreak in America. Initially ZIKV was not considered a dangerous flavivirus as the infections were asymptomatic with only mild complications. But, ... -
SHP2 inhibitors: Recent advancements and potential breakthroughs in cancer therapy
(Brac University, 2022-03)SHP2 (Src homology-2 domain-containing protein tyrosinephosphatase-2) works as a tyrosine phosphatase, to eliminate tyrosine phosphorylation in the non-receptor protein to link many oncogenic signaling pathways including ... -
Signal detection of Rhabdomyolysis and death for galantamine: a pharmacovigilance study
(Brac University, 2023-02)Galantamine is one of the common acetylcholinesterase inhibitors used to treat Alzheimer's disease, a neurodegenerative disorder. This study was conducted to determine the impact of galantamine on mortality rate and ... -
Signal detection of rhabdomyolysis and death for rivastigmine: a pharmacovigilance study
(Brac University, 2023-02)The following study utilized the Food and Drug Administration Adverse Event Reporting System (FAERS) database to determine the AChI inhibitor, rivastigmine’s effect on patient mortality as well as its side effect of ... -
Significance of using Poloxamer 407 and Lactose in ibuprofen in vitro solubility enhancement
(Brac University, 2019-08)Ibuprofen is a widely used NSAID drugs dealing with mild to moderate pain formulated in numerous dosage forms. But ibuprofen has very poor solubility in water associated with minimal drug absorption hence leading to ... -
SIRT6 and cancer stem cells: is there any implication?
(Brac University, 2022-02)Cancer resembles a genetic disease that develops due to the uncontrollable growth of cells in the host body. The most prominent cause of this fatal disease development is the presence of cancer stem cells (CSCs) arise ... -
Solid self-emulsifying drug delivery system of domperidone for improved biopharmaceutical characteristics
(Brac University, 2022-09)The aim of this study was to use a solid-self emulsifying drug delivery system (S-SEDDS) to increase the solubility and dissolution rate of Domperidone (DMP), a poorly soluble, weakly basic anti-emetic medication. ... -
Solubility enhancement of fenofibrate by solid dispersion technique
(BRAC University, 2017-10-07)Solubility of drug is an imperative factor in case of oral drug delivery system to acquire intended drug concentration in systemic circulation in order to attain an efficacious therapeutic response. One of the major ...