Browsing Thesis (Bachelor of Science in Biotechnology) by Author "Sayem, Mohammad"
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A comprehensive in silico investigation into the pathogenic SNPs in RTEL1 gene and their biological consequences
Tanshee, Rifah Rownak (Brac University, 2023-03)Regulator of Telomere Helicase 1 (RTEL1) is a protein-coding gene that encodes an essential DNA helicase which is thought to be involved in preserving the telomere and genetic stability. Germline mutations in the RTEL1 ... -
A computational approach to design putative potential siRNAs for silencing the nucleoprotein and surface glycoprotein gene of MARV
Suraiya, Tasnia Iffat (Brac University, 2023-06)Marburg virus (MARV), a member of the Filoviridae family, is the causal agent of a highly fatal hemorrhagic fever with mortality rates ranging from 23% to 90% in humans. This virus is endemic to central Africa and leads ...