Browsing Thesis (Bachelor of Science in Biotechnology) by Title
Now showing items 107-126 of 255
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Identification of the multi-drug resistant genes in the bacteria isolated from the saliva of smoker oral cancer patients and comparative analysis with smoker normal individuals
(Brac University, 2023-08)Cancer poses a severe threat to world health in the modern period. Cancer is abnormal cell proliferation that can affect different bodily components. Due to cultural behaviors like tobacco consumption and betel nut chewing, ... -
Impact of sunlight on chloramphenicol mediated synthetic and herbal eye drops in terms of antimicrobial activity
(BRAC University, 2017-12)Ocular bacterial infections can cause several eye diseases that have potential impact on human health which is a growing concern worldwide. The use of chloramphenicol synthetic eye drops could provide immense coverage ... -
Implications of unusual non-coding RNAs in human diseases
(Brac University, 2020)Over the last few decades, the occurrences of genetic diseases and the rationale behind them are still under the wheels of research. Researchers have unveiled various causes of genetic disorders and shed light on the ... -
Importance of antigen detection for the screening of COVID-19
(Brac University, 2020-10)Since the beginning of the COVID-19 pandemic, laboratories have been using nucleic acid amplification tests, such as real time reverse transcription polymerase chain reaction (rRT-PCR) assays, to detect SARS-CoV-2, the ... -
In planta transformation of three Bangladeshi tomato varieties with a vacuolar antiporter
(BRAC Univeristy, 2017-04)Salinity is one of the major obstructions in Bangladesh towards achieving maximum crop production. Being a consequence of climate change, soil salinity has rapidly increased over the years without any remedy in sight. Along ... -
In silico analysis of structural complex of HAESA receptor like kinase with PAMP IDA and SERk1 co-receptor
(Brac University, 2019-12)Pattern Triggered Immunity (PTI) is actually identified by the activities of pattern recognition receptors (PRRs), which play the most important role in first layer of plant defense mechanism. During aggression of microbes, ... -
In silico analysis revealed hsa-miR-19a-3p and hsa-miR-19b-3p as two potential inhibitors of EGF mRNA in Breast Cancer
(Brac University, 2024-03)Breast cancer (BrC) is a highly prevalent and often fatal disease affecting both women and, to a lesser extent, men worldwide. There were about 2.3 million new breast cancer cases worldwide in 2020, resulting in approximately ... -
An in silico approach for the identification of clinically significant SNPs in a Drug Metabolizing Gene CYP2C9 and development of Tetra-primer ARMS PCR based genotyping method for CYP2C9*3 (rs1057910)
(Brac University, 2020-08)The role of SNP is an important factor related to drug metabolism. The presence or absence of SNP can significantly alter the effect of the same amount of drug inside the body leading to various unwanted side-effects which ... -
An in Silico approach to multi-epitope subunit vaccine development against SARS COV-2 using Membrane Glycoprotein
(Brac University, 2020)SARS Cov -2, short for Severe Acute Respiratory Syndrome Coronavirus-2 is a + sense zoonotic retrovirus of the Coronaviridae family and is genetically a mutant version of the SARS Cov and is the causal organism of the ... -
In silico comparative study of Zika Virus Proteins and analysis of Membrane glycoprotein M as a candidate for vaccine design
(BRAC Univeristy, 2018-07-26)Zika virus is a (+) RNA virus that has become a major concern of public health in the last few years. It is known to cause microcephaly, reduction of brain circumference along with many type of brain injury in new-borns ... -
In silico design of a multi-epitope vaccine against Lyssavirus Phylogroup II Glycoproteins
(Brac University, 2022-12)The genus of lyssavirus, coming from the family of Rhabdoviridae, has been around since the time of 2300 BC. A ~12kb, negative-sense RNA virus, it is known to be one of the lethal viruses ever encountered by mankind. ... -
In silico drug designing against Klebsiella pneumoniae adhesin protein
(Brac University, 2019-01)Klebsiella pneumoniae, is one of the causative agents of many nosocomial infections. In spite of having a plethora of information on the virulent factors of this bacteria, no definite vaccines have yet been designed or ... -
In Silico Epitope based peptide vaccine designing against yellow fever virus
(BRAC University, 2017-08)The most widely used vaccine for treatment of Yellow Fever patients is YF 17D. It is a live attenuated vaccine derived from Asibi strain. It is administered widely to patients throughout the world but it has few problems ... -
In silico identification of molecular mimicry between T-cell epitopes of borrelia burgdorferi and the human proteome: implications for autoimmune response in Lyme disease
(Brac University, 2022-12)Autoimmune disorder is a dysfunctional immune system in a body, which attacks its own cells. Borrelia burgdorferi, a pathogenic bacterium, shares an intrinsic relation to Lyme disease in humans causing autoreactive responses ... -
In silico modelling and structural dynamics of PSY1R kinase domain and its interaction with SERK1 kinase
(Brac University, 2021-09)Due to plants’ immobility, they are continuously faced with different challenges from their surroundings that also include a wide range of pathogens dealing in the environment. Hence by unraveling the mystery behind how ... -
In silico structural analysis of the complex BRI1 Receptor like Kinase, Pamp Brassinolide and Serk1 Co-Receptor
(Brac University, 2021-04)Plants that are sessile species are constantly associated with exposure to pathogenic organisms abundant in their biosphere. Comprehending the hypothesis next to it would be a significant attempt to study the processes ... -
In Silico structural analysis of the complex PSKR receptor like Kinase, Pamp Phytosulfokine and SERk1 co-receptor
(Brac University, 2021-02)Plants often have to undergo pathogen invasions in nature. Nevertheless, as a result of proficient immune systems owned by the host plants, plant diseases seldom occur. In the process two separate recognition mechanisms ... -
In silico structural analysis, physicochemical characterization and homology modeling of Arabidopsis thaliana Na+/H+ exchanger 1 protein
(BRAC University, 2015-09)Climate changes have detrimental effects on the plants such as an increased susceptibility towards pathogens or ill health leading to food insecurity. This is eminently observed in developing countries such as Bangladesh. ... -
In silico structural analysis, physicochemical characterization and homology modeling of Arabidopsis thaliana Na+/H+ exchanger 2 protein
(BRAC Univeristy, 2017-05)Along with climate change, salinity has a detrimental effect on plants. It can cause susceptibility towards pathogens, halt proper growth and thus lead to food insecurity. Therefore, it is necessary to comprehend the ways ... -
In silico structural analysis, physicochemical characterization and homology modeling of transmembrane protein 43 (TMEM 43)
(BRAC University, 2017-09)Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a rare disease of the heart muscle. ARVC is an inherited condition, which means that it is passed on through families. It is caused by a change or mutation in one ...