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dc.contributor.advisorRipa, Farhana Alam
dc.contributor.authorKarim, Tahira
dc.date.accessioned2024-10-22T08:32:11Z
dc.date.available2024-10-22T08:32:11Z
dc.date.copyright©2024
dc.date.issued2024-02
dc.identifier.otherID 20146045
dc.identifier.urihttp://hdl.handle.net/10361/24385
dc.descriptionThis project report is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2024.en_US
dc.descriptionCataloged from PDF version of project report.
dc.descriptionIncludes bibliographical references (pages 24-30).
dc.description.abstractNypa fruticans wurmb has long been utilized in traditional medicine to treat a variety of illnesses including diarrhea. The study was conducted to evaluate antidiarrheal property of the methanolic fruit pulp extract of N. fruticans (NFS). The antidiarrheal activity of NFS extract tested in an experimental model (Swiss albino mice) of castor oil induced diarrhea in 3 different doses- 200, 400 and 600 mg/kg. A significant (p<0.5) reduction in the frequency of wet stools and delaying the onset of diarrhea as compared with the control group were observed in rodents treated with the methanolic crude extract at doses 400 and 600 mg/kg. However, the effect of increased dose dependently and 600 mg/kg NFS extract produced a comparable effect (66.68%) with the reference drug (Loperamide) in mice. Therefore our result proved that N. fruticans (NFS) has potent antidiarrheal activity. Moreover the investigation's promising findings may provide a framework for further study in this area.en_US
dc.description.statementofresponsibilityTahira Karim
dc.format.extent43 pages
dc.language.isoenen_US
dc.publisherBrac Universityen_US
dc.rightsBrac University project reports are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission.
dc.subjectNypa fruticans wurmben_US
dc.subjectNFSen_US
dc.subjectAntidiarrheal activityen_US
dc.subjectDiarrheal diseaseen_US
dc.subjectDiarrhea treatmenten_US
dc.subjectAntidiarrheal agents
dc.subject.lcshDiarrhea--treatment.
dc.subject.lcshPlant extracts--Therapeutic use.
dc.subject.lcshFruits--Therapeutic use.
dc.subject.lcshMedicinal plants.
dc.subject.lcshAntidiarrheals.
dc.titleIn vivo antidiarrheal activity of Nypa fruticans wurmb fruit pulpen_US
dc.typeProject reporten_US
dc.contributor.departmentSchool of Pharmacy, Brac University
dc.description.degreeB. Pharmacy


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