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dc.contributor.advisorRipa, Farhana Alam
dc.contributor.authorLubaba, Rafiya Rafa
dc.date.accessioned2024-08-22T04:37:42Z
dc.date.available2024-08-22T04:37:42Z
dc.date.copyright©2023
dc.date.issued2023-08
dc.identifier.otherID 19346050
dc.identifier.urihttp://hdl.handle.net/10361/23863
dc.descriptionThis thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023.en_US
dc.descriptionCataloged from the PDF version of thesis.
dc.descriptionIncludes bibliographical references (pages 28-34).
dc.description.abstractThe study explored the analgesic and CNS depressant activities of a methanolic shell extract from Nypa fruticans Wurmb fruit. Methanolic shell extract of N. fruticans Wurmb fruit was acetic acid induced technique was used to test the analgesic efficacy in mice. An evaluation of CNS depressant activity used the hole cross test. Different doses (200, 400, and 600 mg/kg) were administered to mice, and results indicated significant dose-dependent analgesic and CNS depressant activities (p<0.05). The extract exhibited enhanced analgesic effects, achieving 51.16% inhibition at 600 mg/kg, whereas the standard drug Indomethacin achieved 79.54% inhibition. At 600 mg/kg, the extract reduced locomotor activity and exploratory behavior, similar to standard drug diazepam. These findings highlighted the notable analgesic and CNS depressant activities of the methanolic shell extract from N. fruticans Wurmb fruit.en_US
dc.description.statementofresponsibilityRafiya Rafa Lubaba
dc.format.extent47 pages
dc.language.isoenen_US
dc.publisherBrac Universityen_US
dc.rightsBrac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission.
dc.subjectNypa fruticansen_US
dc.subjectWurmb fruiten_US
dc.subjectAnalgesicen_US
dc.subjectCNS depressanten_US
dc.subjectHole cross methoden_US
dc.subject.lcshCentral nervous system depressants
dc.subject.lcshAnalgesics--Toxicology
dc.titleAnalgesic and CNS depressant activities of methanolic shell extract of Nypa fruticans Wurmb fruit in Swiss albino miceen_US
dc.typeThesisen_US
dc.contributor.departmentSchool of Pharmacy, Brac University
dc.description.degreeB. Pharmacy


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