dc.contributor.advisor | Haque, Md. Aminul | |
dc.contributor.author | Rahman, Shaidur | |
dc.date.accessioned | 2024-06-06T06:10:34Z | |
dc.date.available | 2024-06-06T06:10:34Z | |
dc.date.copyright | ©2023 | |
dc.date.copyright | 2023 | |
dc.date.issued | 2023-02 | |
dc.identifier.other | ID: 19146092 | |
dc.identifier.uri | http://hdl.handle.net/10361/23197 | |
dc.description | This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023. | en_US |
dc.description | Cataloged from the PDF version of thesis. | |
dc.description | Includes bibliographical references (pages 24-31). | |
dc.description.abstract | Single nucleotide polymorphism (SNP) can take place in the vitamin D receptor (VDR) gene which can cause alteration in normal procedure of the VDR. Thus, ultimately restricting the work of vitamin D which can be a precursor of various diseases. Four major single nucleotide polymorphisms (SNP) of the VDR gene that are mostly worked with are FokI, TaqI, BsmI and ApaI. This study was done by focusing on the SNP of BsmI (rs1544410) across different populations by taking information from the studies that performed case-control model studies. It was observed after review of different studies that most of the diseases like rheumatoid arthritis, osteoporosis, rickets, autoimmune diseases and other diseases indicated a relation with BsmI polymorphism of VDR gene in different populations with some contradictory reports. But the majority of them got a significant result. Future studies with more detailed work are encouraged considering different ethnic groups. | en_US |
dc.description.statementofresponsibility | Shaidur Rahman | |
dc.format.extent | 42 pages | |
dc.language.iso | en | en_US |
dc.publisher | BRAC University | en_US |
dc.rights | Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. | |
dc.subject | Polymorphism | en_US |
dc.subject | SNP association | en_US |
dc.subject | Vitamin D receptor | en_US |
dc.subject | VDR gene | en_US |
dc.subject | Single Nucleotide Polymorphism | en_US |
dc.subject | rs1544410 | en_US |
dc.subject | Rheumatoid arthritis | en_US |
dc.subject.lcsh | Nuclear receptors (Biochemistry). | |
dc.subject.lcsh | Single nucleotide polymorphisms. | |
dc.subject.lcsh | Genetic polymorphism. | |
dc.subject.lcsh | Rheumatoid arthritis. | |
dc.title | A review on the role of SNP at rs1544410 of VDR gene in different diseases | en_US |
dc.type | Thesis | en_US |
dc.contributor.department | School of Pharmacy, Brac University | |
dc.description.degree | B. Pharmacy | |