A study on the types of Assay used in the British Pharmacopoeia
Abstract
In this study, the most common assay type for the APIs in British Pharmacopoeia
monographs was determined. In addition, any possible patterns in solubility, Log P and pKa
was investigated. Acid base titration, non-aqueous titration and HPLC were found to be the
most common assay types. Also found some other analytical methods like complexometric
titration, redox titration, UV-Vis spectroscopy, microbiological assay have been
recommended. Some pattern in case of solubility was found only; log P and pKa do not
follow any specific orientation based on assay type.