Prevalence and application of an evolving genome editing tool “CRISPR/Cas System” in cancer research and treatment

Abstract

One of the biggest causes of mortality worldwide is cancer. Cancer is one of the most challenging diseases to cure because of its capacity to spread quickly, metastasis, and create diverse tumors as a result of mutagenesis events. The gene editing tool Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) systems and CRISPR-associated (Cas) enzymes have demonstrated enormous potential in the treatment of genome-based disorders, particularly cancer, due to their great precision and efficiency. CRISPR-Cas systems can find fresh targets for brand new prospective anti-cancer therapies thanks to their capacity to purposefully activate or repress genes. The mechanisms of the various kinds of CRISPR-Cas systems are outlined in this paper. This study also covers a number of additional uses for CRISPR-Cas systems in the realm of cancer, including as diagnostic and therapeutic uses.