dc.contributor.advisor | Ashrafi, Sania | |
dc.contributor.author | Sowa, Rodoshi Mahfuz | |
dc.date.accessioned | 2023-04-11T04:07:50Z | |
dc.date.available | 2023-04-11T04:07:50Z | |
dc.date.copyright | 2022 | |
dc.date.issued | 2022-02 | |
dc.identifier.other | ID: 18146086 | |
dc.identifier.uri | http://hdl.handle.net/10361/18135 | |
dc.description | This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. | en_US |
dc.description | Cataloged from PDF version of thesis. | |
dc.description | Includes bibliographical references (pages 52-71). | |
dc.description.abstract | Recently researchers are centered on creating drug-like substance as an elective to the
accessibledrugs with less adverseeffects.Besides, peopleproceed to be influenced by a
fewillnessesbasically due to environmentalstrengths such as drug-fightingorganisms as well
ascontaminations. Lupeol is a natural triterpenoid which along with its derivatives exists in a
considerable quantity in eatablenatural products and vegetables, and medicinal plants. A
plenty of studies about the biological activity of lupeol and its subsidiary derivatives have
been conducted and it has been demonstrated that they have broad pharmacological
possibilitiesinside them specifically or in a roundabout way. There are also some
pharmacokinetic studies, which indicated its bioavailability, absorption, distribution, polarity,
excretion rate, AUC and other pharmacokinetic parameters. Along with some structural
modifications and derivatives, lupeol has shown significant potency in better
pharmacokinetic and pharmacological action in many in-vivo as well as in-vitro studies. The
goal of this survey paper is to collaborate all the major biological capacities of this novel
compound and its subsidiary derivatives along with the mechanisms of action, clinical as well
as preclinical study results, applications in treatment, some limitations and future prospects. | en_US |
dc.description.statementofresponsibility | Rodoshi Mahfuz Sowa | |
dc.format.extent | 71 pages | |
dc.language.iso | en | en_US |
dc.publisher | Brac University | en_US |
dc.rights | Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. | |
dc.subject | Phytochemical | en_US |
dc.subject | Lupeol | en_US |
dc.subject | Analogue | en_US |
dc.subject | Confined | en_US |
dc.subject | Carcinoma | en_US |
dc.subject | Triterpenoid | en_US |
dc.subject | Rodents | en_US |
dc.subject | Anti-Angiogentic | en_US |
dc.subject | Melanoma | en_US |
dc.subject | Clutter | en_US |
dc.subject | Expansion | en_US |
dc.subject | Lipidemia | en_US |
dc.subject | Cyclophosphamide | en_US |
dc.subject | Divergent | en_US |
dc.subject | Hepatoprotective | en_US |
dc.subject.lcsh | Pharmaceutical technology. | |
dc.title | The Pharmacological potential of lupeol and derivatives: A corroborative analysis | en_US |
dc.type | Thesis | en_US |
dc.contributor.department | Department of Pharmacy, Brac University | |
dc.description.degree | B. Pharmacy | |