| dc.contributor.advisor | Sayka Khan, Tanisha Tabassum | |
| dc.contributor.author | Sadia, Mir | |
| dc.date.accessioned | 2022-10-18T04:19:05Z | |
| dc.date.available | 2022-10-18T04:19:05Z | |
| dc.date.copyright | 2022 | |
| dc.date.issued | 2022-02 | |
| dc.identifier.other | ID: 18146057 | |
| dc.identifier.uri | http://hdl.handle.net/10361/17517 | |
| dc.description | This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. | en_US |
| dc.description | Cataloged from PDF version of thesis report. | |
| dc.description | Includes bibliographical references (pages 61-68). | |
| dc.description.abstract | Cancer is one of the leading causes of death around the world. The ability to proliferate at a rapid
rate, metastasize, and form heterogeneous tumors due to mutagenic occurrences renders cancer as
one of the most difficult-to-treat diseases in the world. Owing to its high accuracy and efficiency,
the gene editing tool Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)
systems and CRISPR-associated (Cas) enzymes have shown immense potential in the treatment of
genome-based diseases, especially cancer. The ability to deliberately activate or repress genes,
allows CRISPR-Cas systems to discover novel targets for new potential anti-cancer drugs. In this
review, the mechanism of different classes of CRISPR-Cas systems are summarized. Several other
applications including diagnostic and therapeutic applications of CRISPR-Cas systems in the field
of oncology are also addressed in this review. | en_US |
| dc.description.statementofresponsibility | Mir Sadia | |
| dc.format.extent | 68 Pages | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Brac University | en_US |
| dc.rights | Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. | |
| dc.subject | CRISPR-Cas | en_US |
| dc.subject | Cancer treatment | en_US |
| dc.subject | Immunotherapy | en_US |
| dc.subject | CRISPR applications | en_US |
| dc.subject | Disease models | en_US |
| dc.subject | Oncology | en_US |
| dc.subject.lcsh | Genetic engineering | |
| dc.subject.lcsh | Gene editing--Technological innovations. | |
| dc.subject.lcsh | CRISPR-associated protein 9. | |
| dc.title | A review on CRISPR-Cas system based applications in Oncology | en_US |
| dc.type | Thesis | en_US |
| dc.contributor.department | Department of Pharmacy, Brac University | |
| dc.description.degree | B. Pharmacy | |
