Antimicrobial peptides in skin diseases
Abstract
Skin diseases, including inflammatory and infections, result from disruptions in the skin's
barrier. Antimicrobial peptides (AMPs) have recently gained attention as potential treatments
for inflammatory, soft skin tissue and wound infections. This review discusses AMPs in skin
diseases. It highlights the therapeutic properties of AMPs and their potential utility in treating
skin disorders. Even though only a few AMPs, such as oritavancin and daptomycin, have been
approved for use in clinical trials. Moreover, omiganan, pexiganan, and DPK-060 have also
been studied extensively for treating skin problems. This paper also mentions some strategies
to increase AMPs' clinical trial success rate.