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dc.contributor.advisorHossain, Mohammed Mahboob
dc.contributor.authorRazna, Amrin Islam
dc.date.accessioned2022-08-23T04:10:38Z
dc.date.available2022-08-23T04:10:38Z
dc.date.copyright2022
dc.date.issued2022-02
dc.identifier.otherID: 18276008
dc.identifier.urihttp://hdl.handle.net/10361/17113
dc.descriptionThis thesis report is submitted in partial fulfillment of the requirement for the degree of Master of Science in Biotechnology, 2022.en_US
dc.descriptionCataloged from PDF version of thesis.
dc.descriptionIncludes bibliographical references (pages 89-103).
dc.description.abstractEdible vaccines are edible plants genetically engineered to contain a gene that specifies an antigen or a marker sequence sequence of defective gene or protein. The mucous lining comprises one of the first lines of defense during pathogen attack and a vaccine usually triggers the mucosal immune system of the mucous lining. The dissertation will highlight the development framework of the edible vaccine, the timeframe of development along their proposed uses. The encapsulation of the antigen in the plant vehicles‘ tissues protects the antigen from the acidic nature of the stomach. The immunogen, being in partially intact form, would be able to stimulate an immune response. Edible vaccines could be further used to induce tolerance to allergens. For such cases, the immunogen is in soluble form. Studies have revealed that these vaccines can stimulate the production of secretory IgA along with other antibodies. Currently, six edible vaccines are undergoing clinical trials; however, certain issues need to be solved before their approval. Veterinary edible vaccines have been already approved. Bangladesh has also attempted to design an edible vaccine for pneumonia. It can be inferred that shortly, edible vaccines would be a valuable tool for preventing health conditions.en_US
dc.description.statementofresponsibilityAmrin Islam Razna
dc.format.extent103 Pages
dc.language.isoen_USen_US
dc.publisherBrac Universityen_US
dc.rightsBrac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission.
dc.subjectEdible Vaccinesen_US
dc.subjectSecretory IgAen_US
dc.subjectAntibodiesen_US
dc.subjectTransformationen_US
dc.subjectGM1-ELISAen_US
dc.subject.lcshVaccines--Development
dc.subject.lcshVaccines--Developing countries
dc.titleProgress of edible vaccine developmenten_US
dc.typeThesisen_US
dc.contributor.departmentDepartment of Mathematics and Natural Sciences, Brac University
dc.description.degreeM. Biotechnology


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