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dc.contributor.advisorJamiruddin, Mohd. Raeed
dc.contributor.authorArka, Sadib Md.
dc.date.accessioned2022-01-19T05:10:09Z
dc.date.available2022-01-19T05:10:09Z
dc.date.copyright2020
dc.date.issued2020-01
dc.identifier.otherID 15146005
dc.identifier.urihttp://hdl.handle.net/10361/15956
dc.descriptionThis thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2021.en_US
dc.descriptionCataloged from PDF version of thesis report.
dc.descriptionIncludes bibliographical references (pages 24-32).
dc.description.abstractOsteosarcoma is a type of bone cancer casting huge threat to the human health worldwide. It is a primary bone malignancy with a particularly high incidence rate in children and adolescents relative to other age groups. The etiology of this often aggressive cancer is currently unknown, because complicated structural and numeric genomic rearrangements in cancer cells preclude understanding of tumour development. The aim of the study is to analyze gene expression to identify biomarkers for osteosarcoma. We downloaded and mined two expression profile datasets associated with osteosarcoma from the Gene Expression Omnibus. After data background correction we analyzed the data using R studio software. However, we could not achieve our cherished result due to some package error in the software. Though we could not figure out the possible biomarkers using our data but some studies has been found that gene which take part in antigen presentation and immune process are highly expressed in the escalation of osteosarcoma cell growth the expression genes in all were shown as heatmap. Doing further study of osteosarcoma cell growth, it may help to facilitate the individual management of patients with osteosarcoma after treatment.en_US
dc.description.statementofresponsibilitySadib Md. Arka
dc.format.extent32 pages
dc.language.isoenen_US
dc.publisherBrac Universityen_US
dc.rightsBrac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission.
dc.subjectMicroarray analysisen_US
dc.subjectGene expressionen_US
dc.subjectR softwareen_US
dc.subjectHeatmapen_US
dc.subjectBone canceren_US
dc.subject.lcshOsteosarcoma
dc.subject.lcshOncology
dc.titleA study of Osteosarcoma gene profileen_US
dc.typeThesisen_US
dc.contributor.departmentDepartment of Pharmacy, Brac University
dc.description.degreeB. Pharmacy


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