Investigation of in-vitro biological potential of Methanol extract of Magnolia alba Leaves

Abstract

From immemorial time medicinal plants are used as an important source of medication for ailments and diseases. Now a day it has expanded the source of income also. In this experiment some pharmacological activities were screened from methanol extracted Magnolia alba leaf. Antioxidant properties were identified using DPPH assay. The data from this assay proved the existence of Antioxidant in this plan. Although the IC50 level of experimental plant leaves is comparatively lower than the standard (Ascorbic Acid). Later on, thrombolytic activity also tested, by it demonstrated 19.1% clot lysis which is lower than compared with the standard clopidogrel. Furthermore, evaluation of Cytotoxicity property done by Brine Shrimp Lethality Assay (BLSA). The result showed for Magnolia alba leaves was 7.904% whereas the standard vincristine sulphate showed 3.324%.It has appeared a higher level of cytotoxicity in this experimental plant but the antimicrobial test did not give any significant result though. Exploring new possibilities and expectations is the beauty of research. It seems this study will help to design future researches and discovering a new source of antioxidant, cardiovascular and anticancer drug with more effectiveness and safety.