dc.contributor.advisor | Neelotpol, Dr. Sharmind | |
dc.contributor.author | Khan, Farzana | |
dc.date.accessioned | 2019-01-02T07:58:15Z | |
dc.date.available | 2019-01-02T07:58:15Z | |
dc.date.copyright | 2018 | |
dc.date.issued | 2018-02 | |
dc.identifier.other | ID 13146039 | |
dc.identifier.uri | http://hdl.handle.net/10361/11068 | |
dc.description | This project report is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2018. | en_US |
dc.description | Catalogued from PDF version of project report. | |
dc.description | Includes bibliographical references (page 29-35). | |
dc.description.abstract | Geophagy is the practice of consuming earth materials such as Calabash chalk. This practice is
widespread in diverse countries in Asia and Africa by both the sexes and the different age groups
of people. Many women and children who ingest Calabash chalk develop dependency. Many
pregnant women take Calabash chalk as a remedy from morning sickness and some people also
take it to lessen stomach dressing. However, harmful contents of calabash chalk such as Lead,
Aluminum Silicate Hydroxide were found responsible for affecting developing brain of fetus and
also, they affect the kidneys, nervous system, and reproductive system. Therefore, the aim of this
study is to evaluate the effect of Calabash chalk on the biochemical and histopathological
changes in spleen, kidney and liver of second generation Albino Rats. To conduct this study four
groups of rats were treated with only water and 0.5ml, 1.0ml and 1.ml dose of Calabash Chalk.
After 33 days blood and organ samples were collected for further examination. In this study,
although no significant results were found in case of blood parameters, several changes such as
possible hepatocellular injury in kidney cells and sinusoidal dilution in liver cells were found in
rats due to the treatment with Calabash Chalk. Cellular carcinoma was also suspected in spleen
cells. | en_US |
dc.description.statementofresponsibility | Farzana Khan | |
dc.format.extent | 35 pages | |
dc.language.iso | en | en_US |
dc.publisher | BRAC University | en_US |
dc.rights | BRAC University project reports are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. | |
dc.subject | Calabash chalk | en_US |
dc.subject | Pregnancy | en_US |
dc.subject.lcsh | Food habits--Psychological aspects. | |
dc.title | Practice of geophagy: effects of calabash chalk on liver, kidney and spleen in swiss albino rats | en_US |
dc.type | Project report | en_US |
dc.contributor.department | Department of Pharmacy, BRAC University | |
dc.description.degree | B. Pharmacy | |