Thesis (Master of Science in Biotechnology): Recent submissions
Now showing items 1-20 of 158
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Genomic analysis of the correlation between CRISPR self-targeting spacers and prophage-related pathogenicity in Vibrio cholerae and Staphylococcus aureus
(Brac University, 2024-10)The interactions between bacteria and phages are intricate and dynamic, manifesting through two main life cycles: the lytic cycle, in which phages destroy their hosts via cell lysis, and the lysogenic cycle, where phage ... -
RISK 6 transcriptomic signature for diagnosis and treatment monitoring of extrapulmonary tuberculosis
(Brac University, 2024)Diagnosing extrapulmonary tuberculosis (EPTB) is challenging due to the diverse clinical manifestations of the disease and the requirement for invasive sampling and specialized processing. Moreover, current methods lack ... -
Potential causative agents of biofilm-induced Cholera: an in vitro approach
(Brac University, 2024-06)Cholera, while easily treatable, is extremely common across many parts of the world, especially in the regions close to water bodies. The bacteria responsible, Vibrio cholerae, has an interesting affinity to forming ... -
Comparative analysis of machine learning models for the prediction of asthma disease among the cardiovascular disease patients
(Brac University, 2024-06)Cardiovascular diseases (CVD) are a leading cause of morbidity and mortality worldwide, and recent studies have highlighted a potential association between CVD and the development of asthma. Predicting the likelihood of ... -
Hypovitaminosis D: a modifiable risk factor for noncommunicable diseases
(Brac University, 2022-04)Over the years, a broad spectrum of non-communicable diseases (NCDs), including osteoporosis, asthma, diabetes, cancer, hypertension, cardiovascular diseases, chronic kidney and liver diseases have been linked to poor ... -
Isolation, identification and characterization of plastic degrading Gut bacteria from Zophobas atratus larvae
(Brac University, 2024-04)Plastic pollution has become a major environmental concern globally, and novel and eco-friendly approaches like bioremediation are essential to mitigate the impact. This study investigated the biodegradation of three common ... -
Molecular profiling, antibiotic susceptibility patterns and pathogenic traits of ESBL producing Acinetobacter baumannii Isolated from wastewater discharges from Goranchatbari sub-catchment area in Dhaka city
(Brac University, 2024-05)Acinetobacter baumannii is one of the six pathogens for which new antibiotic formulations must be developed, as recommended by the World Health Organization. In this study, 28 wastewater samples were collected from the ... -
Inducible Clindamycin resistance among clinically isolated Methicillin resistant Staphylococcus aureus (MRSA) at tertiary care hospitals in Bangladesh
(Brac University, 2024-05)Upon being virtually resistant to all β lactam antibiotics, Methicillin Resistant Staphylococcus aureus (MRSA) infections are being commonly treated by clindamycin due to various benefits. But due to the inducible Macrolide ... -
An overview of phage therapy as an alternative option of MDR bacteria and possible future of COVID-19 treatment
(Brac University, 2022-09)One of the greatest difficulties that humanity will confront in the near future is antibiotic resistance. (Bacterio) phage therapy is a valuable therapeutic alternative to antibiotics, and while the concept is almost as ... -
Detection of genetic diversity of SARS-CoV-2 in wastewater to monitor COVID-19 transmission
(Brac University, 2023-08)Coronavirus Disease 2019 (COVID-19), an infectious respiratory disease caused by the viral strain, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a distinct cause of the global burden and a ... -
Association of MTHFR rs1801133, PEMT rs4244593, CHKA rs7928739, VNTRs IL-1RN intron 2 and NOS3 intron 4 polymorphisms with unexplained intrauterine fetal death in Bangladeshi population
(Brac University, 2024-04)This case-control study aimed to analyze interaction between increased risk of Intrauterine Fetal Death in Bangladeshi pregnant women and Single Nucleotide Polymorphism (SNP) of MTHFR (rs1801133), PEMT (rs4244593), CHKA ... -
Isolation and molecular identification of salt tolerant probiotic bacteria and their impacts on rice (Oryza sativa) seedlings
(Brac University, 2021-10)Soil salinity is a serious problem in the coastal areas of Bangladesh. It is the main barrier to attain sustainability in crop production in those particular areas. Moreover, the situation is getting worse along with time. ... -
Genomic characterization of environmental Klebsiella pneumoniae through whole genome sequencing
(Brac University, 2024-06)Klebsiella pneumoniae poses a significant public health threat due to its high antibiotic resistance and its role in severe infections, especially in healthcare settings. Investigating environmental K. pneumoniae is crucial ... -
Finding etiological factors for the onset of neonatal sepsis diagnosed in tertiary care hospitals in Dhaka, Bangladesh
(Brac University, 2024-06)With an incidence rate of 76.8/1000 live births, or 36% of all neonatal fatalities, neonatal sepsis is one of the main causes of infant mortality in Bangladesh. Research from a few lower-middle-income (LMI) countries has ... -
Diversity of salmonella typhi-phages in Dhaka city through whole genome sequencing
(Brac University, 2024-06)Bacteriophages and their hosts form a vast ecosystem, with bacteria evolving diverse defense mechanisms against phage infection while phages simultaneously develop strategies to overcome these defenses. Limited data on ... -
Exploring of deletion mutation causative for Duchenne Muscular Dystrophy (DMD) in Bangladesh cohort
(Brac University, 2022-10)Background: Duchenne muscular dystrophy (DMD) is an inherited genetic disorder resulting progressive skeletal, respiratory and cardiac muscle weakness. DMD is caused by a variety of mutations in DMD gene located on the X ... -
Evaluation of endometriosis risk factors, symptoms, and clinical treatments in Bangladesh: a cross-sectional study
(Brac University, 2024-03)In Bangladesh, endometriosis is one of the leading causes of infertility. Endometriosis causes infertility in 25–50% of women, and it affects one out of every ten women of reproductive age. Unfortunately, many of these ... -
Mutagenic effects of pesticides on Enteric Bacteria and their role in the rise of antimicrobial resistance (AMR)
(Brac University, 2023-12)Microbial antibiotic resistance threatens world health dangerously. Moreover the non-antibiotic stressors have also contributed to bacterial antibiotic resistance. Pesticides affect bacterial antibiotic resistance, and ... -
Downregulation of SOCS1 gene in the development of Guillain-Barré syndrome
(Brac University, 2023-12)Guillain-Barre syndrome (GBS), is a post-infectious disorder of the peripheral nervous system mediated by an aberrant immune response where cytokines play an imperative role in disease pathogenesis. Suppressor of cytokine ... -
An investigation into the present condition and biomolecular activities of Bangladeshi seaweed with deadly diseases: a review
(Brac University, 2024-01)The potential for therapeutic and nutraceutical applications of marine algae is unparalleled because they contain several novel molecules and other bioactive compounds. Many known and unknown marine algae are abundant in ...
