Master of Science in Biotechnology
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Renal function assessment for CKD in Type-2 Diabetes patients of Bangladesh: a cross-sectional study
(BRAC University, 2024-11)Chronic Kidney Disease (CKD) is a major long-term complication of Type 2 diabetes mellitus. The aim of this study was to determine the prevalence of CKD among patients with Type 2 diabetes (T2D) and its associated ... -
Association of LEPR gene rs1137100 (Lys109Arg) & rs1137101 (Gln223Arg) polymorphisms with Type 2 Diabetes Mellitus in young Bangladeshi population: a pilot study
(BRAC University, 2024-12)"Background: Youth-onset Type 2 Diabetes Mellitus (T2DM) is an emerging global public health concern. Polymorphisms in the LEPR (leptin receptor) gene, specifically rs1137100 (Lys109Arg) and rs1137101 (Gln223Arg) have ... -
Exploring the association among breast cancer risk factors, biomarker profiles, and tumor stages: a study from Dhaka, Bangladesh
(BRAC University, 2024-11)Breast cancer is one of the most common types of cancer worldwide and continues to be a global public health concern. According to GLOBOCAN estimates, 19% of 68.7 million new breast cancer cases were diagnosed in 2022, ... -
Assessment of antibiotic resistance profiles and pathogenic traits of Escherichia coli isolates in Dhaka city's municipal water supply
(BRAC University, 2024-12)Antimicrobial resistance (AMR) in Escherichia coli is a growing global threat, with significant public health implications. This study evaluated municipal household water in Dhaka North, Bangladesh, revealing fecal ... -
Cosmetics and skin cancer: a review of risks, prevention and treatment
(BRAC University, 2021-06)Skin cancer, including Non-melanoma skin cancer (NMSC) and melanoma, constitutes a real global health challenge. This review paper discusses epidemiological aspects of skin cancer, its risk factors, pathophysiology, and ... -
Genetic diversity of potato accessions revealed by simple sequence repeat makers
(BRAC University, 2023-09)Potato is one of the most economically important food crops worldwide. Information on the genetic diversity of a germplasm bank is necessary for potato breeding. In this study, genetic diversity of 62 potato accessions ... -
Synergistic effect of bacteriophage with antibiotic in the eradication of vibrio cholerae infection: an in-vivo analysis in mice model
(Brac University, 2024-08)Cholera remains a significant global health threat, especially in regions like Bangladesh with annual outbreaks. The causative agent, Vibrio cholerae, thrives in aquatic environments and forms biofilms, complicating ... -
Production, purification and characterization of cellulase from bacteria
(Brac University, 2022-09)Microorganisms isolated from soil samples that showed growth on carboxymethylcellulose (CMC) agar media were selected for enzyme production by utilizing carbon sources such as CMC, leaves and paper. Biochemical analysis ... -
The emergence of antimicrobial resistance genes over the years and their geographic bias
(Brac University, 2022-09)Antimicrobial agents have played a very intrinsic role in human and animal health since the beginning of the world. However, our irresponsibility has made this life saver, equally deadly. This study shows how much AMR has ... -
Decoding the role of uncharacterized Helicobacter Pylori proteins on differentially expressed genes in GC Pathogenesis
(Brac University, 2024-09)Gastric cancer (GC) is one of the most frequent and deadly cancers worldwide. Helicobacter pylori (H. pylori), a GC-associated bacterium, is critical to gastric pathogenesis. However, the specific molecular mechanisms ... -
Resuscitation of bacterial biofilm by sunlight: effects on different enteropathogenic bacteria
(Brac University, 2021-08)It is an established fact that most bacteria go through motile and sessile form during its lifetime. This transition has significant roles in seasonal outbreaks of certain bacterial diseases and bacterial pathogenesis. ... -
Genomic analysis of the correlation between CRISPR self-targeting spacers and prophage-related pathogenicity in Vibrio cholerae and Staphylococcus aureus
(Brac University, 2024-10)The interactions between bacteria and phages are intricate and dynamic, manifesting through two main life cycles: the lytic cycle, in which phages destroy their hosts via cell lysis, and the lysogenic cycle, where phage ... -
RISK 6 transcriptomic signature for diagnosis and treatment monitoring of extrapulmonary tuberculosis
(Brac University, 2024)Diagnosing extrapulmonary tuberculosis (EPTB) is challenging due to the diverse clinical manifestations of the disease and the requirement for invasive sampling and specialized processing. Moreover, current methods lack ... -
Potential causative agents of biofilm-induced Cholera: an in vitro approach
(Brac University, 2024-06)Cholera, while easily treatable, is extremely common across many parts of the world, especially in the regions close to water bodies. The bacteria responsible, Vibrio cholerae, has an interesting affinity to forming ... -
Comparative analysis of machine learning models for the prediction of asthma disease among the cardiovascular disease patients
(Brac University, 2024-06)Cardiovascular diseases (CVD) are a leading cause of morbidity and mortality worldwide, and recent studies have highlighted a potential association between CVD and the development of asthma. Predicting the likelihood of ... -
Hypovitaminosis D: a modifiable risk factor for noncommunicable diseases
(Brac University, 2022-04)Over the years, a broad spectrum of non-communicable diseases (NCDs), including osteoporosis, asthma, diabetes, cancer, hypertension, cardiovascular diseases, chronic kidney and liver diseases have been linked to poor ... -
Isolation, identification and characterization of plastic degrading Gut bacteria from Zophobas atratus larvae
(Brac University, 2024-04)Plastic pollution has become a major environmental concern globally, and novel and eco-friendly approaches like bioremediation are essential to mitigate the impact. This study investigated the biodegradation of three common ... -
Molecular profiling, antibiotic susceptibility patterns and pathogenic traits of ESBL producing Acinetobacter baumannii Isolated from wastewater discharges from Goranchatbari sub-catchment area in Dhaka city
(Brac University, 2024-05)Acinetobacter baumannii is one of the six pathogens for which new antibiotic formulations must be developed, as recommended by the World Health Organization. In this study, 28 wastewater samples were collected from the ... -
Inducible Clindamycin resistance among clinically isolated Methicillin resistant Staphylococcus aureus (MRSA) at tertiary care hospitals in Bangladesh
(Brac University, 2024-05)Upon being virtually resistant to all β lactam antibiotics, Methicillin Resistant Staphylococcus aureus (MRSA) infections are being commonly treated by clindamycin due to various benefits. But due to the inducible Macrolide ... -
An overview of phage therapy as an alternative option of MDR bacteria and possible future of COVID-19 treatment
(Brac University, 2022-09)One of the greatest difficulties that humanity will confront in the near future is antibiotic resistance. (Bacterio) phage therapy is a valuable therapeutic alternative to antibiotics, and while the concept is almost as ...
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