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Genetic disorders associated with mutations in bHLH transcription factors: a review
(Brac University, 2022-11)
bHLH proteins belong to a superfamily of proteins characterized by one of the largest dimerized
transcriptional proteins. The main role of bHLH protein is in the developmental processes. They
function as transcriptional ...
In silico identification of molecular mimicry between T-cell epitopes of borrelia burgdorferi and the human proteome: implications for autoimmune response in Lyme disease
(Brac University, 2022-12)
Autoimmune disorder is a dysfunctional immune system in a body, which attacks its own cells. Borrelia burgdorferi, a pathogenic bacterium, shares an intrinsic relation to Lyme disease in humans causing autoreactive responses ...
CRISPR/Cas9 genome editing to treat sickle cell disease
(Brac University, 2022-11)
The most prevalent inherited blood condition, Sickle Cell Disease (SCD) causes excruciating
pain, permanent organ damage including liver, heart, and kidney also causes an untimely
death. There is currently a dearth of ...
Relation of chest HRCT scan findings with hematological, biochemical, and immunological parameters of hospitalized Covid-19 patients in a tertiary hospital in Chattogram city
(Brac University, 2023-03)
The chest HRCT scan can be used as a diagnostic tool for COVID-19 disease in cases of clinical suspicion, false-negative RT-PCR, or unavailability of the test. The study aimed to investigate the relation of HRCT findings ...
Demystifying lanthanomes: a pangenomic approach
(Brac University, 2023-04)
Certain members of multi-generic, gram negative proteobacteria (newly named pseudomonatota)
have recently been reported to be capable of successfully utilizing the catalytic potential of
lanthanide metals for the efficient ...