Browsing by Subject "Solubility"
Now showing items 1-6 of 6
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Development of UV-Vis spectroscopic method for determining effect of solvent on solubility of Vitamin C and Vitamin E
(Brac University, 2020-01)This study was done to observe effect of solvent on solubility of vitamins. Vitamins studied included vitamin C (water soluble) and vitamin E (fat soluble). The solvents used included acetonitrile and distilled water. The ... -
Domperidone: A literature based review on pharmacokinetic control using different drug delivery strategies
(Brac University, 2021-01)Domperidone (DMP), a potent gastroprokinetic and antiemetic drug, exhibits poor aqueous solubility and extensive first-pass metabolism. Therefore, to develop its oral preparations with optimized absorption and ... -
Method development of oil solubility test of Aceclofenac
(Brac University, 2019-10)The aim of the study was to develop a method that would allow the solubility testing of Aceclofenac in different oils. The main target was to find a suitable method by using commercially available drugs like olive oil. The ... -
Significance of using Poloxamer 407 and Lactose in ibuprofen in vitro solubility enhancement
(Brac University, 2019-08)Ibuprofen is a widely used NSAID drugs dealing with mild to moderate pain formulated in numerous dosage forms. But ibuprofen has very poor solubility in water associated with minimal drug absorption hence leading to ... -
Solid self-emulsifying drug delivery system of domperidone for improved biopharmaceutical characteristics
(Brac University, 2022-09)The aim of this study was to use a solid-self emulsifying drug delivery system (S-SEDDS) to increase the solubility and dissolution rate of Domperidone (DMP), a poorly soluble, weakly basic anti-emetic medication. ... -
Solubility of Ibuprofen with Poloxamer 407 and L-leucine in water and ethanol co-solvent
(Brac University, 2019-08)Ibuprofen is a drug with very poor aqueous solubility and high permeability. Its poor aqueous solubility is one of the major problems when formulating a dosage form with it. This study was conducted by considering its poor ...
