Browsing by Subject "Polymorphism"
Now showing items 1-7 of 7
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Association of XRCC1 and XPD polymorphism with risk of prostate cancer in Bangladesh population
(Brac University, 2023-02)This study examined the effects of the X-ray cross-complementing gene 1 (XRCC1) Arg194Trp and Xeroderma pigmentosum group D (XPD) Lys751Gln polymorphisms on the risk, severity, and clinical parameter of prostate cancer in ... -
A review on association of genetic polymorphism with thyroid hormone level leading to different diseases
(Brac University, 2024-04)The study delved into the investigation of CYP27B1 hydroxylase, a vital enzyme responsible for converting 25-hydroxyvitamin D3 (25OHD3) into 1,25(OH)2D3, the most potent natural form of vitamin D crucial for immune modulation ... -
A review on relationship of SNP at rs2228570 of VDR gene and different diseases in different populations
(Brac University, 2023-02)Multiple disorders are caused by mutations in the vitamin D receptor (VDR) gene. The VDR gene directs the body to manufacture vitamin D receptor protein (VDR). This vitamin D receptor is engaged in vitamin D-mediated ... -
A review on Single Nucleotide Polymorphism (SNPs) and their effect on cancer risk in South Asian population
(Brac University, 2021-01)Cancer is one of the leading causes of death and currently 1 in 6 death is known to occur due to cancer. Each type of cancer is linked to variations occurring in the gene. Any form of genetic variation which disrupts the ... -
A review on the association of SNP at rs731236 of VDR Gene and different diseases in various ethnicity
(Brac University, 2023-02)There is much of information on vitamin D's importance in bone metabolism, but less is known about how it affects other organs or systems. Vitamin D is receptor is found in the kidney, pancreas, prostate, gut, platelets, ... -
A review on the role of SNP at rs1544410 of VDR gene in different diseases
(Brac University, 2023-02)Single nucleotide polymorphism (SNP) can take place in the vitamin D receptor (VDR) gene which can cause alteration in normal procedure of the VDR. Thus, ultimately restricting the work of vitamin D which can be a precursor ... -
Screening of G6PD Mutation and polymorphism using high resolution melt curve analysis
(BRAC University, 2017)Glucose-6-phosphate dehydrogenase (G6PD) deficiency is one of the most common X-linked recessive disorders resulting from the defect of a single gene encoding an enzyme called G6PD. G6PD enzymes catalyzes the conversion ...
