Browsing by Subject "POLG"

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Functional analysis of depression associated proteins: role of TRK, BDNF, CYP2B6, POLG, PICK1 Biomarkers for early detection and treatment of depression

Jurashe, Partha Sanjana (BRAC University, 2018-09)

Psychiatric diseases relentlessly distress the ability of work also productivity of a person’s life. Considering the phenotypic unpredictability amongst patients, it is very hard to understand the pathogenesis. The study ...
Mutation in DNA polymerase γ: mitochondrial disorders

Hossain, Sadman Sanjid (Brac University, 2022)

Together with key components of the mitochondrial DNA (mtDNA) replication machinery, DNA polymerase γ (POLG) replicates the human mitochondrial genome. Defects in mtDNA replication or nucleotide metabolism result in mtDNA ...