Browsing by Subject "Molecular genetics"
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A comprehensive in silico investigation into the pathogenic SNPs in RTEL1 gene and their biological consequences
(Brac University, 2023-03)Regulator of Telomere Helicase 1 (RTEL1) is a protein-coding gene that encodes an essential DNA helicase which is thought to be involved in preserving the telomere and genetic stability. Germline mutations in the RTEL1 ... -
CRISPR: a revolutionary tool for modeling and treating cancer and Duchenne muscular dystrophy
(Brac University, 2022-04)The novel CRISPR/Cas system is an effective and widely used gene-editing tool that has created the opportunity to study gene function and understand the pathogenic mechanisms underlying various genetic disorders. It has ...
